Biomarker discovery in colon cancer with advanced metabolomics
Official title: Biomarker discovery in colon cancer through next-generation metabolomics
Funded at Panome Bio INC · NIH-11404018 · Data updated 2026-11-12
A new project will use advanced chemical analysis to find blood- and tissue-based markers that indicate colon cancer and its progression.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Panome Bio INC NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 2, 2025 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,164,167 |
| NIH project number | 5R44CA295318-02 |
| Project ID | NIH-11404018 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with colon cancer or suspected colon cancer who could contribute samples or participate in future biomarker validation studies.
✕Less likely to help
Patients without colon cancer or those not contributing samples may not directly benefit.
What this research studies
This project aims to identify reliable biomarkers for colon cancer by applying untargeted metabolomics with LC/MS to large samples. The team will develop and test software to better distinguish true metabolite signals from noise, improving accuracy for clinical use. Results could lead to better diagnostics and personalized treatment decisions for people with colon cancer.
Why it matters
Potential benefit: If successful, patients could receive earlier and more precise tests and personalized treatment plans.
How similar studies have gone: Similar metabolomics approaches have yielded promising biomarkers in cancer, but untargeted methods remain challenging and are being actively developed.
Where this research is happening
-
Panome Bio INC
Saint Louis, United States Active
Researchers
- Principal investigator: Stancliffe, Ethan — Panome Bio INC
- Study coordinator: Stancliffe, Ethan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.