NIH-funded research NIH-funded research

AMPDECIDE: Helping Veterans choose amputation level with personalized outcome information

Official title: The AMPDECIDE Patient Decision Aids: Empowering Veteran Participation in Personalized Amputation Level Decision-making

Funded at VA Puget Sound Healthcare System · NIH-11395975 · Data updated 2026-11-12

A doctor helps a veteran facing leg amputation learn personalized risks and likely outcomes for different amputation levels to guide their care choices.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Puget Sound Healthcare System
NIH-funded
Lab location1 site (Seattle, United States)
Project startOctober 1, 2024
Project endSeptember 30, 2029
Funding year2026
NIH project number5I01RX005018-03
Project IDNIH-11395975 on NIH RePORTER

Who could benefit from this research

Could help

Veterans facing dysvascular lower-extremity amputation considering different amputation levels.

Less likely to help

Veterans who are not involved in decision-making or who are not considering amputation level choices may not directly benefit.

What this research studies

This project creates patient-friendly decision aids that present personalized risks and likely functional outcomes for each amputation level in veterans with diabetes or PAD. The goal is to support shared decision-making so veterans can align their choice with what matters most to them, such as mobility, independence, and quality of life. The approach focuses on clear information, value-driven discussions, and tools that help patients express their priorities during clinical visits. Participating veterans will be engaged in the development and use of these decision aids to ensure relevance and usefulness in real-world care.

Why it matters

Potential benefit: Veterans could make more informed, values-based decisions about amputation level, potentially improving function and QoL.

How similar studies have gone: Prior studies suggest patient decision aids can improve engagement and satisfaction in SDM, though personalized amputation-level decisions are less explored.

Where this research is happening

  • VA Puget Sound Healthcare System
    Seattle, United States
    Active

Researchers

  • Principal investigator: Henderson, Alison Wilhelm — VA Puget Sound Healthcare System
  • Study coordinator: Henderson, Alison Wilhelm

Related research

Other NIH-funded projects on the same topics.

  • Decision aids to help Veterans choose the best amputation level

    This project will build easy-to-use tools that show Veterans their personalized chances of outcomes for different lower-leg amputation levels so they can choose what fits their goals.

    NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-11206915

  • Helping Veterans make informed decisions about amputation levels

    This study is all about helping Veterans who have had leg amputations because of diabetes or circulation issues by giving them personalized information to help them make the best choices for their health and lifestyle, so they can feel more in control and improve their quality of life.

    NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-10994031

  • Advancing Shared Decision Making for Stroke Prevention in Atrial Fibrillation

    Aims to combine data from three big trials to understand how decision aids help people with atrial fibrillation choose anticoagulation to prevent stroke, in a patient-centered way.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11445391

  • Understanding how octopuses integrate sensory information and make decisions

    This study is exploring how octopuses use their arms to grip things by looking closely at their nervous system and movements, which could help us understand their amazing abilities better.

    NIH research Michigan State University · East Lansing, United States · NIH-9949982

  • An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya

    A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11625516

  • NoviGuide for Newborn Care in Pakistan

    A small NIH grant to test a pocket-sized decision support tool for nurses and doctors to improve newborn care in Pakistan.

    NIH research Aga Khan University (Pakistan) · Karachi, Pakistan · NIH-11624823

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.