NIH-funded research NIH-funded research

Decision aids to help Veterans choose the best amputation level

Official title: The AMPDECIDE Patient Decision Aids: Empowering Veteran Participation in Personalized Amputation Level Decision-making

Funded at VA Puget Sound Healthcare System · NIH-11206915 · Data updated 2026-11-12

This project will build easy-to-use tools that show Veterans their personalized chances of outcomes for different lower-leg amputation levels so they can choose what fits their goals.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Puget Sound Healthcare System
NIH-funded
Lab location1 site (Seattle, United States)
Project startOctober 1, 2024
Project endSeptember 30, 2029
Funding year2025
NIH project number5I01RX005018-02
Project IDNIH-11206915 on NIH RePORTER

Who could benefit from this research

Could help

Veterans facing a dysvascular lower-limb amputation (due to diabetes or peripheral artery disease) who are making decisions about amputation level.

Less likely to help

People not facing amputation, those with traumatic or non-dysvascular amputations, or those unable to engage in shared decision-making may not benefit from these specific tools.

What this research studies

If you are a Veteran facing a lower-extremity amputation because of diabetes or peripheral artery disease, this project will provide decision aids that show your personalized risks for outcomes like survival, reamputation, and mobility at each amputation level. The team will combine your clinical information with existing outcome data to generate individualized risk estimates and guide conversations about what matters most to you. Veterans and clinicians will use these tools to support shared decision-making and clarify patient priorities and preferences. The decision aids will be tested and refined with Veteran feedback at the VA Puget Sound Health Care System before broader use.

Why it matters

Potential benefit: Could help Veterans pick an amputation level that better matches their values, improving mobility, quality of life, and satisfaction with care.

How similar studies have gone: Patient decision aids have improved shared decision-making in other surgical decisions, but personalized decision aids focused on amputation level are relatively new and not widely tested.

Where this research is happening

  • VA Puget Sound Healthcare System
    Seattle, United States
    Active

Researchers

  • Principal investigator: Henderson, Alison Wilhelm — VA Puget Sound Healthcare System
  • Study coordinator: Henderson, Alison Wilhelm

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.