NIH-funded research R21 grant

AHEAD: How early-life diet shapes kids’ health and teeth

Official title: AHEAD: Adolescent Health and the EArly-life Dietary Exposome: Developing a Metabolomics-based Index of Healthy Eating to predict children's health trajectories

Funded at Columbia University Health Sciences · NIH-11356836 · Data updated 2026-11-12

A study will look at what kids eat and how it changes their health and teeth over time by using metabolomics to build a healthy-eating index for children.

More Metabolomics research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 1, 2026
Project endJuly 31, 2028
Funding year2026
Award (this year)$471,123
NIH project number1R21DE036066-01
Project IDNIH-11356836 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include children and adolescents across age ranges (0-20s) whose caregivers are interested in monitoring diet quality and health trajectories.

Less likely to help

Children without access to ongoing dietary data collection or those not engaging with metabolomic sampling may see limited direct benefit.

What this research studies

This project follows children from early life to later ages to see how diet and environmental exposures relate to oral and overall health. Researchers will collect dietary data and biological samples to create a metabolomics-based index that reflects healthy versus cariogenic eating. The goal is to link diet quality with trajectories of dental caries, obesity, and related conditions, helping families understand which foods may support long-term health. The study emphasizes practical implications for everyday childhood nutrition and health planning.

Why it matters

Potential benefit: If successful, it could lead to a simple tool to guide healthier eating in children and reduce future dental and metabolic problems.

How similar studies have gone: Prior work shows diet and metabolic signatures relate to health outcomes, though this exact metabolomics index for childhood diet is novel.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Custodio-Lumsden, Christie Lauren — Columbia University Health Sciences
  • Study coordinator: Custodio-Lumsden, Christie Lauren

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.