A smarter, cost-effective smoking cessation package for people with HIV in clinical care
Official title: Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care
Funded at New York University · NIH-11353883 · Data updated 2026-11-12
A study will test a combination of support methods to help people living with HIV quit smoking more effectively in real clinical settings.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $700,744 |
| NIH project number | 5R01CA268932-05 |
| Project ID | NIH-11353883 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV who smoke and receive care in clinical settings.
✕Less likely to help
If you are not a current smoker or not engaged in HIV clinical care, you may not benefit.
What this research studies
If you have HIV and smoke, this project aims to find a sustainable package of help that fits into regular HIV care. It uses a method that tests several components at once, so researchers can see which mix works best at helping people quit. The components include motivational conversations, peer support, text reminders, and nicotine-related therapies, tested in a way that shows how each part contributes. The goal is a scalable program that clinics can adopt to boost long-term abstinence from smoking.
Why it matters
Potential benefit: If successful, this package could make quitting easier for people with HIV and lead to better health outcomes.
How similar studies have gone: Previous components showed promise, but their combined effectiveness in an optimization framework is being tested.
Where this research is happening
-
New York University
New York, United States Active
Researchers
- Principal investigator: Cantrell, Jennifer — New York University
- Study coordinator: Cantrell, Jennifer
Related research
Other NIH-funded projects on the same topics.
-
Social stress and smoking: why disadvantaged young adults struggle to quit
This grant looks at how daily social stress affects if and when disadvantaged young adults who smoke can quit and stay quit.
-
I-STOP: a mobile health program to help people with HIV quit smoking
A smartphone-based program designed to help people with HIV quit smoking in a sustainable, affordable way.
-
Smoking cessation help for people with HIV in South Africa
A program is being tested to help people living with HIV in South Africa quit smoking in ways that fit low-resource clinics and show good value.
-
Mobile tools to understand how sleep affects quitting smoking
This project uses a smartphone to track sleep and smoking in lower-income adults trying to quit to find how sleep patterns relate to staying smoke-free.
-
Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
-
Peer-led smoking-cessation program for public housing residents
A peer-led program with eight group sessions plus nicotine replacement therapy is tested on adults living in public housing to help them quit smoking.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.