A place-based approach to geographic disparities in lung transplant
Funded at Cleveland Clinic Lerner Com-Cwru · NIH-11364924 · Data updated 2026-11-12
Aiming to understand how where people live affects lung transplant outcomes and to improve survival for transplant patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $671,658 |
| NIH project number | 5R01HL164660-04 |
| Project ID | NIH-11364924 on NIH RePORTER |
Who could benefit from this research
✓Could help
People who have received a lung transplant and whose outcomes may be influenced by where they live.
✕Less likely to help
Patients outside the geographic regions studied or those without access to post-transplant care tied to place may see limited direct benefit.
What this research studies
This grant explores how a patient’s geographic and social environment influences post-transplant lung function and survival. Researchers will map patients to their local census tracts and link these places to health outcomes using geographic information science. The project seeks to uncover mechanisms by which place-based factors contribute to regional survival differences and to guide personalized care and policy changes. The work uses large, multicenter data to identify patterns that could help tailor risk stratification and interventions for diverse patient communities.
Why it matters
Potential benefit: If successful, patients could receive more personalized follow-up plans and policies could be developed to reduce geographic survival gaps after lung transplant.
How similar studies have gone: Previous work has shown geographic disparities in transplant outcomes; this study builds on observational patterns with a place-based framework.
Where this research is happening
-
Cleveland Clinic Lerner Com-Cwru
Cleveland, United States Active
Researchers
- Principal investigator: Tsuang, Wayne M — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Tsuang, Wayne M
Related research
Other NIH-funded projects on the same topics.
-
Exercise-based frailty program for people awaiting lung transplants
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-
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-
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-
Vaccination responses in lung transplant patients
This grant studies how people who have received lung transplants respond to COVID-19 vaccines and why their antibody responses may be limited.
-
The Post-Lung Transplant Aging in Immune Cells in Donor Lungs
This grant explores how aging donor lungs affect lung transplant outcomes by studying immune cells called alveolar macrophages.
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Predictors of Lung Transplant Success and Costs
This study looks at what pre-transplant patient factors and biology predict a smooth recovery and lower costs after lung transplant.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.