Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Impact of Preoperative Physical Activity on Bladder Cancer Surgery Outcomes

Official title: Prospective Randomized Interventional Study to Investigate the Impact of Preoperative Physical Activity on Perioperative Morbidity Following Radical Cystectomy

Run by Ludwig-Maximilians - University of Munich · NCT06806059 · Data updated 2026-11-12

This study is testing if being more physically active before bladder cancer surgery can help patients recover better and have fewer complications.

More Urothelial Carcinoma Bladder trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment146 (estimated)
SponsorLudwig-Maximilians - University of Munich
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Munich, Bavaria)
StatusRecruiting
StartedNovember 29, 2024
Main results expectedNovember 29, 2026
Study endsNovember 29, 2027
Registry record updatedApril 27, 2026
Trial IDNCT06806059 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients diagnosed with muscle-invasive urothelial carcinoma of the bladder who are scheduled for radical cystectomy.

Probably not a fit

Patients who require walking aids, have depression, or suffer from significant cardiovascular, neuromuscular, or orthopedic disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of preoperative physical activity on patients undergoing radical cystectomy for muscle-invasive bladder cancer. It aims to determine whether increased physical fitness prior to surgery can reduce perioperative morbidity. Conducted at the University of Munich, the study will follow a prospective randomized design over three years, focusing on patients with urothelial carcinoma of the bladder. The primary endpoint is to assess the impact of physical activity on complications associated with the surgery.

Why it matters

Potential benefit: If successful, this approach could lead to improved recovery and reduced complications for bladder cancer patients undergoing surgery.

How similar studies have gone: Previous studies on prehabilitation in cancer patients have shown improvements in strength and fitness, but results regarding complications and mortality have been mixed, making this approach both relevant and somewhat novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Urothelial cell cancer of the bladder
* Treatment with radical cystectomy

Exclusion Criteria:

* Need for walking aid
* Depression
* cardiovascular, neuromuscular or orthopaedic deficites / disorders
* Time to surgery \< 3 Weeks

Where it's running

  • Department of Urology, LMU Hospital
    Munich, Bavaria, Germany
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.