Impact of Preoperative Physical Activity on Bladder Cancer Surgery Outcomes
Official title: Prospective Randomized Interventional Study to Investigate the Impact of Preoperative Physical Activity on Perioperative Morbidity Following Radical Cystectomy
Run by Ludwig-Maximilians - University of Munich · NCT06806059 · Data updated 2026-11-12
This study is testing if being more physically active before bladder cancer surgery can help patients recover better and have fewer complications.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 146 (estimated) |
| Sponsor | Ludwig-Maximilians - University of Munich Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Munich, Bavaria) |
| Status | Recruiting |
| Started | November 29, 2024 |
| Main results expected | November 29, 2026 |
| Study ends | November 29, 2027 |
| Registry record updated | April 27, 2026 |
| Trial ID | NCT06806059 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients diagnosed with muscle-invasive urothelial carcinoma of the bladder who are scheduled for radical cystectomy.
✕Probably not a fit
Patients who require walking aids, have depression, or suffer from significant cardiovascular, neuromuscular, or orthopedic disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effects of preoperative physical activity on patients undergoing radical cystectomy for muscle-invasive bladder cancer. It aims to determine whether increased physical fitness prior to surgery can reduce perioperative morbidity. Conducted at the University of Munich, the study will follow a prospective randomized design over three years, focusing on patients with urothelial carcinoma of the bladder. The primary endpoint is to assess the impact of physical activity on complications associated with the surgery.
Why it matters
Potential benefit: If successful, this approach could lead to improved recovery and reduced complications for bladder cancer patients undergoing surgery.
How similar studies have gone: Previous studies on prehabilitation in cancer patients have shown improvements in strength and fitness, but results regarding complications and mortality have been mixed, making this approach both relevant and somewhat novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Urothelial cell cancer of the bladder * Treatment with radical cystectomy Exclusion Criteria: * Need for walking aid * Depression * cardiovascular, neuromuscular or orthopaedic deficites / disorders * Time to surgery \< 3 Weeks
Where it's running
-
Department of Urology, LMU Hospital
Munich, Bavaria, Germany Recruiting
Study contacts
- Study coordinator: Yannic Volz, PD Dr. med.
- Email: yannic.volz@med.uni-muenchen.de
- Phone: +49 089 4400 75970
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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BL-M07D1: T-bren vs standard platinum chemo for HER2-expressing metastatic urothelial cancer after anti-PD-(L)1 therapy
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This trial will try a Nectin‑4–targeted radioactive drug called [225Ac]Ac‑AKY‑1189 in adults with locally advanced or metastatic solid tumors, including certain bladder, breast, lung, and cervical cancers.
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Combination treatment for advanced urothelial carcinoma
This study is testing a new combination of a drug called AM80 with standard chemotherapy and immunotherapy to see if it helps people with advanced bladder cancer feel better and live longer.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.