Condition
Tuberous Sclerosis Complex (TSC) clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Tuberous Sclerosis Complex (TSC) clinical trials that are recruiting, at sites in 4 countries (most in Australia (2), Italy (1), Romania (1)). By phase: Phase 1 (1), Phase 1/2 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 4Countries
Newest Tuberous Sclerosis Complex (TSC) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Periodontal Health in Rare Kidney Conditions and Controls | — | Bucharest | Recruiting | May 8, 2026 |
| Full‑spectrum cannabis extract for refractory epilepsy in tuberous sclerosis | Phase 3 | Madrid | Recruiting | Feb 11, 2026 |
| Sapu003 with or without exemestane for advanced mTOR-sensitive solid tumors | Phase 1 | Adelaide | Recruiting | Jan 27, 2026 |
| Paxalisib added to treat certain brain conditions with seizures | Phase 1/2 | Heidelberg, Victoria and 1 other locations | Recruiting | Dec 17, 2025 |
| Observing kidney issues in children with tuberous sclerosis | — | Bologna | Recruiting | Jan 8, 2025 |
All recruiting trials (5)
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Periodontal Health in Rare Kidney Conditions and Controls
This study tests how common periodontitis is in people with rare kidney disorders and compares it to CKD patients and people without kidney disease.
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Full‑spectrum cannabis extract for refractory epilepsy in tuberous sclerosis
This trial tests whether a full‑spectrum cannabis extract (YCJ-01) can reduce seizures in people with tuberous sclerosis complex who have hard‑to‑control epilepsy.
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Sapu003 with or without exemestane for advanced mTOR-sensitive solid tumors
This phase 1b test will try weekly IV Sapu003, given with exemestane for HR+/HER2- breast cancer or alone for other mTOR-sensitive advanced tumors, to see if it's safe and how your body handles it.
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Paxalisib added to treat certain brain conditions with seizures
This study tests whether Paxalisib (SVG103) is safe and tolerable in adults with FCD-II, TSC, or HME who have frequent seizures.
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Observing kidney issues in children with tuberous sclerosis
This study looks at kidney problems, like cysts and tumors, in children with tuberous sclerosis to better understand how common these issues are.
Related topics
Quick answers
How many Tuberous Sclerosis Complex (TSC) clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in Australia (2 trials), Italy (1 trial), Romania (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.