Condition

Sensorineural Hearing Loss clinical trials and research

• 18Clinical trials
• 18NIH research projects
• 9Countries

Newest Sensorineural Hearing Loss clinical trials

All recruiting trials (18)

• Biomarkers in Congenital Hearing Loss: Alpha-Tectorin, IL-10, and Thiol-Disulfide Balance in Children

  This observational study tests whether levels of alpha-tectorin, IL-10, and thiol-disulfide balance differ in children with congenital sensorineural hearing loss (with cochlear implants or hearing aids) compared with healthy children.

  Recruiting Harran University · Sanliurfa · NCT07860580

• Anatomy-based fitting for single-sided deaf CI users

  This study tests whether anatomy-based fitting changes how well adults with single-sided deafness use a cochlear implant to understand speech in noise and to enjoy music.

  Recruiting University Hospital, Antwerp · Antwerp · NCT07703800

• Long-term outcomes of MED-EL SONATA 2 Cochlear Implants in real life

  This study looks at long-term results from people who received a SONATA 2 cochlear implant to see how well it works in everyday life.

  Recruiting MED-EL Elektromedizinische Geräte GmbH · Madrid and 1 other locations · NCT07697911

• Anatomy-Based Fitting for People with a Cochlear Implant and Hearing Aid

  This study tests whether an anatomy-based frequency distribution works better than the default one for adults with a cochlear implant and a contralateral hearing aid.

  Recruiting at 2 sites Universitair Ziekenhuis Brussel · Antwerp and 1 other locations · NCT07691853

• Biomarkers linked to congenital CMV using newborn blood spots

  Researchers will test protein and RNA markers in dried blood spots from newborns to see if they can identify congenital CMV sequelae early.

  Recruiting at 2 sites Copenhagen University Hospital, Rigshospitalet · Copenhagen and 1 other locations · NCT07635368

• Yiyuancong treatment for sudden sensorineural hearing loss

  This trial will test whether adding Yiyuancong, a traditional Chinese medicine formula, to standard care helps adults with sudden sensorineural hearing loss recover more hearing.

  Recruiting at 5 sites Guangdong Provincial People's Hospital · Guangzhou, Guangdong and 4 other locations · NCT07505667

• N-acetylcysteine to prevent cisplatin-related hearing loss

  This study tests whether N-acetylcysteine (NAC) can prevent hearing loss in adults receiving high-dose cisplatin chemotherapy.

  Recruiting Phase 2 Siriraj Hospital · Bangkok, Bangkoknoi · NCT07364747

• Preserving residual hearing during cochlear implant surgery.

  This trial tests whether inserting the implant through the round window and using a straight lateral-wall electrode helps preserve remaining hearing in adults with severe sensorineural hearing loss who are receiving an Advanced Bionics cochlear implant.

  Recruiting UMC Utrecht · Utrecht · NCT07146841

• Perceptual adaptation after cochlear implantation

  This trial will try different frequency maps in adults who just received a cochlear implant in one ear to see which map improves sound quality, device use, and speech understanding.

  Recruiting NYU Langone Health · New York, New York · NCT07039435

• Long-term follow-up of a cochlear implant with a drug-eluting electrode

  This study looks at how a special cochlear implant that releases a medication affects hearing over time in people with hearing loss.

  Recruiting at 3 sites Cochlear · Englewood, Colorado and 2 other locations · NCT06936449

• Exploring the genetic factors of hearing loss in Turner Syndrome

  This study is trying to find out how genetics might affect hearing loss in people with Turner Syndrome to help develop new treatments.

  Recruiting Gødstrup Hospital · Herning · NCT06507007

• Vestibular and balance testing for children with sensorineural hearing loss

  This project will test if common balance and inner-ear tests can find vestibular problems in children aged 3–10 who have sensorineural hearing loss.

  Recruiting Gødstrup Hospital · Herning · NCT06229717

• Long-term follow-up of infants with congenital CMV in New York State

  This study follows infants in New York who have congenital CMV to see how the infection affects their development, hearing, and vision as they grow up.

  Recruiting Stony Brook University · Stony Brook, New York · NCT06226558

• Investigating how clear speech affects listening effort and memory in older adults with hearing loss

  This study is testing how clear speech affects how hard older adults with hearing loss have to work to listen and remember what they hear.

  Recruiting University of Utah · Salt Lake City, Utah · NCT06053190

• Investigating immune responses and biomarkers in patients receiving cochlear implants

  This study is trying to understand why some people lose their remaining hearing after getting cochlear implants by looking at their blood and inner ear samples.

  Recruiting University Hospital, Montpellier · Montpellier · NCT05670158

• Anatomy-based fitting for cochlear implant users

  This study tests a new way to fit cochlear implants using CT scans of the ear to see if it helps people with severe hearing loss hear better compared to the usual fitting method.

  Recruiting at 2 sites Universitair Ziekenhuis Brussel · Brussels, Brussels Capital and 1 other locations · NCT05451628

• Measuring brain responses to visual stimuli in people with hearing loss

  This study is testing how the brain responds to visual images in people with hearing loss to see if it can help improve treatments for their condition.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05107466

• Evaluating Listening Effort in Cochlear Implant Users

  This study tests how well adults with cochlear implants can focus on sounds compared to people with normal hearing to see what makes listening harder for them in busy environments.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT04733950

NIH-funded research (18)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding why phantom sounds and intolerance to sounds happen after hearing loss

  This grant investigates why some adults with hearing loss experience tinnitus, hyperacusis, and trouble ignoring background noise, and how brain changes relate to these symptoms.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11397425

• Biomarkers linked to cochlear nerve damage in adults with sensorineural hearing loss

  A project to find biological markers of cochlear nerve damage and see how they relate to hearing problems like difficulty hearing in noise and tinnitus in adults with hearing loss.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11397421

• Cochlear nerve connections and hearing loss in human temporal bones

  A large, patient-facing research effort analyzes how nerve connections in the inner ear deteriorate in people with sensorineural hearing loss by studying post-mortem human temporal bones.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11397420

• Cochlear nerve disease and how it affects hearing in models of hearing loss

  This grant studies how damage to the nerves of the ear happens and how it affects hearing in noisy places, using animal models to inform future human therapies.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11397415

• Sensorineural hearing loss and how it affects understanding speech

  This project explores why people with similar hearing loss have different abilities to understand speech, especially in noisy places, and aims to uncover the brain and ear mechanisms behind these differences.

  NIH research Purdue University · West Lafayette, United States · NIH-11334302

• Understanding why some people with hearing loss can’t understand speech in noise

  This grant studies why some people with hearing loss can’t understand speech in noisy environments, even when they can hear it, to identify new ways to help them hear and understand better.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11327287

• Why some adults get tinnitus, sound sensitivity, or trouble hearing in noisy places

  Researchers will link ear-nerve damage and the brain's overreaction to explain tinnitus, sound sensitivity, and difficulty hearing in background noise in adults with sensorineural hearing loss.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11158999

• Inner‑ear nerve damage and its link to trouble hearing in noise, tinnitus, and sound sensitivity

  Looks for hidden inner‑ear nerve damage that may explain trouble understanding speech in noise, tinnitus, and sound sensitivity in adults with sensorineural hearing loss.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11158997

• Loss of inner-ear nerve connections and how it affects hearing test results

  This project looks at donated human inner ears to learn how loss of nerve connections affects hearing and speech understanding in people with sensorineural hearing loss.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11158995

• Hidden nerve loss in the inner ear that makes hearing in noisy places harder

  This project uses animal models and human-focused hearing tests to link hidden nerve loss inside the ear with trouble understanding speech in noisy environments.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11158990

• Understanding why some people with hearing loss struggle to comprehend speech.

  This study is looking at how certain physical changes in the ear affect how well people with hearing loss, especially those using hearing aids, can understand speech in noisy places, and it hopes to find ways to help improve their listening experience.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11104418

• Understanding Hearing Loss and Speech in Noisy Environments

  This project aims to understand why some people with hearing loss find it harder to understand speech, especially in noisy places.

  NIH research Purdue University · West Lafayette, United States · NIH-11101397

• How hearing loss affects the brain's ability to locate sounds

  This study is looking at how hearing loss affects the ability to tell where sounds are coming from, using rabbits to help us understand this better, so we can learn more about why people with hearing loss might struggle with sound location.

  NIH research Ohio University Athens · Athens, United States · NIH-10974304

• Exploring how listening effort affects understanding and memory in older adults with hearing loss

  This study is looking at how people with hearing loss struggle to understand speech and how that can affect their memory, especially in older adults, to help find better ways to support their communication skills.

  NIH research University of Utah · Salt Lake City, United States · NIH-10952179

• Understanding how certain immune cells affect hearing loss caused by a virus.

  This study is looking at how certain immune cells in the inner ear help with hearing and how a virus called cytomegalovirus (CMV) might affect them, which could lead to hearing loss, with the goal of finding better ways to treat this issue.

  NIH research University of Utah · Salt Lake City, United States · NIH-10930030

• Understanding hearing loss through non-invasive tests

  This study is looking at how different kinds of hearing loss impact your ability to understand speech, especially when there's background noise, and it aims to find new ways to help people with hearing loss by using special tests that go beyond regular hearing checks.

  NIH research Purdue University · West Lafayette, United States · NIH-10916292

• Understanding how viruses cause hearing loss

  This study is looking at how certain viruses, like the mumps virus, can cause hearing loss by affecting the inner ear, using mice to help understand what happens and how we might treat it better in the future.

  NIH research Stanford University · Stanford, United States · NIH-10906810

• Exploring how listening effort affects memory and understanding in older adults with hearing loss

  This study is looking at how people with hearing loss struggle to understand speech and how that can affect their memory, and it aims to find ways to help improve their listening and thinking skills in everyday conversations.

  NIH research University of Utah · Salt Lake City, United States · NIH-10782437

Related topics

Quick answers

How many Sensorineural Hearing Loss clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (5 trials), Belgium (3 trials), Denmark (3 trials), France (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →