Exploring the genetic factors of hearing loss in Turner Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the genetic and epigenetic factors associated with sensorineural hearing loss in individuals with Turner Syndrome. By examining DNA methylation patterns and RNA expression profiles, the study seeks to identify potential links between these genetic markers and inner ear dysfunction. Participants will undergo a series of tests, including ear examinations, hearing assessments, balance evaluations, blood tests, and imaging scans, to gather comprehensive data on their inner ear health. The ultimate goal is to uncover insights that could lead to innovative treatments for hearing loss.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age between 18 and 60 years old

Exclusion Criteria:

* Contraindications for the MRI or CBCT
* Serious medical disorders
* Neurological or psychiatric disorders of any kind
* Use of medication that is known to influence inner ear function
* Medical history with dizziness or hearing problems (controls only)

Where it's running

• ENT department of Gødstrup Hospital
  Herning, Denmark Recruiting

Study contacts

• Principal investigator: Therese Ovesen, Prof — University Clinic of Flavour, Balance and Sleep
• Study coordinator: Louise Hill-Madsen, MD
• Email: lohill@rm.dk
• Phone: 20282635

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.