Condition
Refractory Melanoma clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Refractory Melanoma clinical trials that are recruiting, in United States. By phase: Phase 1 (2), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 1Country
Newest Refractory Melanoma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| DOC1021 dendritic cell vaccine for refractory melanoma | Phase 1/2 | Birmingham, Alabama and 7 other locations | Recruiting | Dec 17, 2025 |
| Testing a new treatment using engineered NK cells for advanced melanoma | Phase 1 | Houston, Texas | Recruiting | Oct 28, 2024 |
| Treatment of advanced solid tumors with IACS-6274 and other medications | Phase 1 | Houston, Texas | Recruiting | Sep 10, 2021 |
All recruiting trials (3)
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DOC1021 dendritic cell vaccine for refractory melanoma
This trial tests whether DOC1021, a personalized vaccine made from your own tumor and immune cells combined with weekly peginterferon (pIFN), is safe and can shrink tumors in people whose melanoma stopped responding to prior treatments including anti‑PD‑1 drugs.
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Testing a new treatment using engineered NK cells for advanced melanoma
This study is testing a new treatment using specially engineered immune cells to see if it can help people with advanced melanoma who haven't responded to other treatments.
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Treatment of advanced solid tumors with IACS-6274 and other medications
This study is testing a new drug called IACS-6274, alone and with other medications, to see how well it can help people with advanced solid tumors and what the safest dose is.
Related topics
Quick answers
How many Refractory Melanoma clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.