Condition
Refractory Lupus Nephritis clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Refractory Lupus Nephritis clinical trials that are recruiting, at sites in 2 countries (most in China (3), United States (1)). By phase: Phase 1/2 (2), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest Refractory Lupus Nephritis clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Long-term follow-up after KYV-101 (CAR T) treatment | — | Denver, Colorado | Recruiting | Feb 11, 2026 |
| Umbilical cord blood CD19-BCMA CAR T cell treatment for refractory lupus nephritis, systemic sclerosis, and Sjögren's with pulmonary hypertension | Phase 1/2 | Beijing, Beijing Municipality | Recruiting | Apr 27, 2025 |
| CD19-BCMA CAR T cell therapy for difficult-to-treat autoimmune diseases | Phase 1/2 | Beijing, China,Beijing | Recruiting | Apr 27, 2025 |
| Combination treatment for difficult-to-treat lupus | Phase 1 | Guangzhou, Guangdomg | Recruiting | Nov 6, 2024 |
All recruiting trials (4)
-
Long-term follow-up after KYV-101 (CAR T) treatment
This follow-up will test how long KYV-101 CAR T cells persist and record any delayed side effects in people who previously received KYV-101 for autoimmune diseases like lupus nephritis, myasthenia gravis, stiff person syndrome, rheumatoid arthritis, or multiple sclerosis.
-
Umbilical cord blood CD19-BCMA CAR T cell treatment for refractory lupus nephritis, systemic sclerosis, and Sjögren's with pulmonary hypertension
This treatment will try umbilical cord blood–derived CD19‑BCMA CAR T cells in people with refractory lupus nephritis, systemic sclerosis, or primary Sjögren's syndrome with pulmonary hypertension who have not responded to standard therapies.
-
CD19-BCMA CAR T cell therapy for difficult-to-treat autoimmune diseases
This study is testing a new CAR T cell therapy to see if it can help people with tough autoimmune diseases like lupus nephritis, systemic sclerosis, and Sjogren's syndrome who haven't found relief with regular treatments.
-
Combination treatment for difficult-to-treat lupus
This study is testing a new combination treatment with NK010 or NK042 and rituximab to see if it helps people with hard-to-treat lupus feel better.
Related topics
Quick answers
How many Refractory Lupus Nephritis clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (3 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.