Condition

Refractory Systemic Lupus Erythematosus clinical trials and research

• 5Clinical trials
• 2Countries

Newest Refractory Systemic Lupus Erythematosus clinical trials

All recruiting trials (5)

• IASO207 injections for active refractory SLE (first-in-human)

  This early-stage study tests a new in vivo CAR-T therapy called IASO207 to see if it is safe and potentially helpful for adults with active, treatment-resistant SLE.

  Recruiting Early Phase 1 Peking University People's Hospital · Beijing · NCT07617740

• Biomarker-guided CAR-T target selection for refractory lupus

  This trial tests whether using a lab-based immune profile to pick CD19- or BCMA-targeted CAR-T can help adults with refractory lupus, including lupus nephritis, who have not responded to standard treatments.

  Recruiting Phase 1/2 Beijing Biotech · Shenzhen, Guangdong · NCT07523542

• CD19 CAR-T therapy for refractory lupus in adults

  This trial tests autologous CD19 CAR-T cells to see if they are safe and tolerable for adults with refractory systemic lupus erythematosus.

  Recruiting Phase 1 Vinmec Research Institute of Stem Cell and Gene Technology · Hanoi · NCT07432334

• Combination treatment for difficult-to-treat lupus

  This study is testing a new combination treatment with NK010 or NK042 and rituximab to see if it helps people with hard-to-treat lupus feel better.

  Recruiting Phase 1 Guangdong Provincial People's Hospital · Guangzhou, Guangdomg · NCT06676631

• CAR-T cell therapy for patients with refractory systemic lupus erythematosus

  This study is testing a new CAR-T cell therapy to see if it can help people with hard-to-treat lupus feel better and improve their symptoms.

  Recruiting Peking University Third Hospital · Beijing, Beijing Municipality · NCT06513429

Related topics

Quick answers

How many Refractory Systemic Lupus Erythematosus clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in China (4 trials), Vietnam (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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