Condition
Preoperative Anxiety clinical trials and research
As of November 12, 2026, Find a Trial lists 18 Preoperative Anxiety clinical trials that are recruiting, at sites in 12 countries (most in Turkey (Türkiye) (7), United States (2), Taiwan (1)). By phase: Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 18Clinical trials
- 12Countries
Newest Preoperative Anxiety clinical trials
All recruiting trials (18)
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Virtual Reality storytelling versus a storybook to ease dental anxiety in children
This study tests whether watching a VR dental story or reading the same story aloud by a dentist helps 6- to 10-year-old Arabic-speaking children feel calmer before dental visits.
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Positive affirmations and imagery to ease preoperative anxiety before joint replacement
This study tests whether guided imagery and positive affirmations can reduce anxiety in adults waiting for knee or hip replacement surgery.
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Aromatherapy for Preoperative Anxiety, Postoperative Pain, and Patient Experience
This study tests whether aromatherapy helps reduce preoperative anxiety and postoperative pain and improves the overall patient experience for adults undergoing surgery.
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Does an Enhanced Recovery After Surgery (ERAS) plan reduce preoperative anxiety and improve 1-year patient-reported outcomes in orthopedic patients?
This study tests whether an ERAS program can lower preoperative anxiety and improve long-term patient-reported outcomes after orthopedic surgery.
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Live parent-child video interaction or cartoon watching to ease emergence agitation in preschoolers
This study tests whether live video calls with a parent or watching cartoons during preoperative transfer can reduce anxiety before anesthesia and agitation after surgery in 2- to 6-year-olds undergoing elective procedures.
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VR preparation for kids before surgery
A small study tests whether a virtual reality tour of the hospital before surgery helps kids aged 3–12 feel less anxious and more cooperative.
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Cartoons and mobile games to ease preoperative anxiety in children with appendicitis
This randomized trial tests whether watching cartoons or playing mobile games for 10 minutes before surgery can reduce anxiety and fear in kids aged 7–12 with appendicitis.
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Intranasal dexmedetomidine versus oral midazolam for premedication in children having elective inguinal or urological surgery
This trial will test whether intranasal dexmedetomidine or oral midazolam works better to calm children aged 2–10 before elective inguinal or urological surgery.
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Does preoperative melatonin improve recovery after gallbladder removal?
This study tests whether giving melatonin before gallbladder removal helps people recover better after surgery.
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Daily screen time and pre-surgery anxiety in 2–5 year olds
We will see if children's daily screen time is linked to how anxious they feel right before elective surgery for kids aged 2 to 5.
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Personal versus hospital-provided dolls to comfort preschoolers during adenoidectomy or tonsillectomy
This tests whether a child's own doll or a hospital-provided doll reduces preoperative anxiety and emergence delirium in 3–7-year-old girls having elective adenoidectomy or tonsillectomy.
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Ride-on toy car transfer for preschool boys going to the operating room
This trial will see if moving boys aged 3–7 to the operating room in a ride-on toy car reduces preoperative anxiety and emergence delirium compared with a standard stretcher.
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Virtual reality tools to ease preoperative anxiety in adults awaiting elective surgery
This study tests whether co-designed virtual reality educational and distraction videos can reduce preoperative anxiety in adults having planned surgery, compared with usual care.
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Virtual reality to reduce anxiety before MR-guided focused ultrasound for essential tremor
This study tests whether watching a short virtual reality video can lower pre-treatment anxiety in adults having MRgFUS for medication-refractory essential tremor.
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Virtual reality to reduce anxiety and improve vital signs and satisfaction for women having gynecologic cancer surgery
This study will try a short virtual reality relaxation session before open gynecologic cancer surgery to reduce anxiety and help stabilize heart rate, blood pressure, and patient satisfaction.
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Using dexmedetomidine and esketamine for sedation in young children before surgery
This study tests if a combination of two medications, dexmedetomidine and esketamine, can help young children feel calm and relaxed before surgery.
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Using virtual reality to reduce anxiety in patients before interventional radiology procedures
This study tests if using virtual reality to watch calming videos can help reduce anxiety in patients getting CT-guided biopsies compared to regular preoperative care.
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Comparing two doses of oral melatonin to reduce anxiety in children before surgery
This study is testing if two different doses of melatonin can help reduce anxiety in children aged 4 to 14 before they have surgery.
Related topics
Quick answers
How many Preoperative Anxiety clinical trials are recruiting right now?
18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 12 countries. The most sites are in Turkey (Türkiye) (7 trials), United States (2 trials), Taiwan (1 trial), Hong Kong (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.