Condition
PFO - Patent Foramen Ovale clinical trials and research
As of November 12, 2026, Find a Trial lists 6 PFO - Patent Foramen Ovale clinical trials that are recruiting, at sites in 13 countries (most in United States (3), Netherlands (1), China (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 13Countries
Newest PFO - Patent Foramen Ovale clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| P3 Occluder System for closing a heart opening (PFO) after stroke | — | Belgrade | Recruiting | Jul 13, 2026 |
| Non-invasive detection of right-to-left shunts with the SONAS headband | — | Nieuwegein, Utrecht | Recruiting | Feb 17, 2026 |
| Percutaneous repair of the atrial septum using the P3 Occluder System for PFO closure | — | Los Angeles, California and 4 other locations | Recruiting | Sep 15, 2025 |
| Registry for Abbott's heart devices | — | Los Angeles, California and 35 other locations | Recruiting | Sep 19, 2024 |
| Comparing biodegradable versus metal PFO occluders for people with migraine | — | Beijing, Beijing Municipality and 1 other locations | Recruiting | Jan 12, 2024 |
| Using a special device to close a heart opening to prevent strokes | — | Tucson, Arizona and 44 other locations | Recruiting | Jan 29, 2019 |
All recruiting trials (6)
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P3 Occluder System for closing a heart opening (PFO) after stroke
We are testing the P3 Occluder System to see if it safely and effectively closes a patent foramen ovale in adults who had a stroke related to their heart opening.
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Non-invasive detection of right-to-left shunts with the SONAS headband
This will test whether the SONAS headband can find right-to-left shunts in adults with hereditary hemorrhagic telangiectasia (HHT) who are already having a bubble heart ultrasound (TTCE).
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Percutaneous repair of the atrial septum using the P3 Occluder System for PFO closure
This trial tests the P3 Occluder System to close a patent foramen ovale (PFO) in adults 18–65 who have had a stroke that may be linked to their PFO.
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Registry for Abbott's heart devices
This study is collecting information to see how safe and effective Abbott's heart devices are for patients getting them implanted in real-life hospital settings.
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Comparing biodegradable versus metal PFO occluders for people with migraine
We will test whether a biodegradable heart occluder works better than a metal occluder to reduce migraine symptoms in adults with a patent foramen ovale.
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Using a special device to close a heart opening to prevent strokes
This study is testing a special device to close a heart opening in people who have had a stroke to see if it can help prevent future strokes.
Related topics
Quick answers
How many PFO - Patent Foramen Ovale clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 13 countries. The most sites are in United States (3 trials), Netherlands (1 trial), China (1 trial), Serbia (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.