Condition

Cryptogenic Stroke clinical trials and research

• 8Clinical trials
• 14Countries

Newest Cryptogenic Stroke clinical trials

All recruiting trials (8)

• Long-term outcomes after PFO closure at Severance Hospital

  This registry tests how well percutaneous PFO closure works over the long term and what factors predict residual shunt, new atrial fibrillation, or other outcomes in adults who had the procedure.

  Recruiting Yonsei University · Seoul · NCT07724171

• P3 Occluder System for closing a heart opening (PFO) after stroke

  We are testing the P3 Occluder System to see if it safely and effectively closes a patent foramen ovale in adults who had a stroke related to their heart opening.

  Recruiting Recross Cardio, Inc. · Belgrade · NCT07698951

• Percutaneous repair of the atrial septum using the P3 Occluder System for PFO closure

  This trial tests the P3 Occluder System to close a patent foramen ovale (PFO) in adults 18–65 who have had a stroke that may be linked to their PFO.

  Recruiting at 5 sites Recross Cardio, Inc. · Los Angeles, California and 4 other locations · NCT07172464

• Transcatheter closure versus medical therapy for PFO in older adults

  This tests whether closing a patent foramen ovale (PFO) with a catheter plus usual medicines prevents another unexplained (cryptogenic) stroke in people over 60 better than medicines alone.

  Recruiting Institut universitaire de cardiologie et de pneumologie de Québec, University Laval · Québec, Quebec and 1 other locations · NCT05907694

• Evaluating Cera™ devices for closing heart openings in stroke patients

  This study is testing a new device to see if it can safely close heart openings in stroke patients and work as well as other options available.

  Recruiting at 7 sites Lifetech Scientific (Shenzhen) Co., Ltd. · Beijing, Beijing Municipality and 13 other locations · NCT05774288

• Using smartwatches and Holter monitors to find hidden atrial fibrillation in stroke patients

  This study is testing if using smartwatches and Holter monitors can help find hidden cases of atrial fibrillation in stroke patients aged 55 and older better than the usual 30-day monitoring.

  Recruiting Hospital Universitari Vall d'Hebron Research Institute · Barcelona, Catalonia · NCT05565781

• Testing a new device for closing a heart defect related to stroke

  This study is testing a new device to close a heart defect in patients who have had a stroke to see if it works as well as other approved devices.

  Recruiting at 8 sites Encore Medical Inc. · Little Rock, Arkansas and 7 other locations · NCT05537753

• Observing patients with BIOTRONIK Implantable Cardiac Monitors

  This study looks at how well the BIOMONITOR III and similar heart monitors work and keep patients safe over time.

  Recruiting at 23 sites Biotronik SE & Co. KG · Adelaide and 30 other locations · NCT04075084

Related topics

Quick answers

How many Cryptogenic Stroke clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in Spain (2 trials), United States (2 trials), China (1 trial), Canada (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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