Condition

Pancreatic Cancer Non-resectable clinical trials and research

• 13Clinical trials
• 1New in 30 days
• 7Countries

Newest Pancreatic Cancer Non-resectable clinical trials

All recruiting trials (13)

• Intra-arterial Y-90 Radioembolization for unresectable pancreatic cancer

  This study tests whether delivering Yttrium-90 microspheres directly into the arteries feeding unresectable pancreatic tumors is safe and tolerable while looking for early signs of effect.

  Recruiting Phase 1 National Medical Research Radiological Centre of the Ministry of Health of Russia · Obninsk · NCT07898683

• Microwave Ablation Feasibility for pancreatic and liver cancers guided by endoscopic ultrasound

  This study tests whether an ultrasound-guided microwave ablation device can be safely and effectively used in adults with locally advanced, unresectable, or metastatic pancreatic or liver cancers.

  Recruiting Banner Health · Gilbert, Arizona and 5 other locations · NCT07817147

• EUS-guided pancreaticobiliary procedures with the RIVOS access device

  This study tests how the RIVOS EUS access device performs during interventional procedures for pancreatic and bile duct problems in adults.

  Recruiting Orlando Health, Inc. · Orlando, Florida · NCT07696572

• SBRT plus maintenance therapy vs maintenance therapy alone in advanced pancreatic cancer

  This trial tests whether adding targeted SBRT to ongoing maintenance therapy helps people with unresectable pancreatic cancer live longer than maintenance therapy alone.

  Recruiting Phase 2 Shandong Cancer Hospital and Institute · Jinan, Shandong · NCT07600268

• New way to deliver Gemcitabine directly to pancreatic tumors in non-resectable pancreatic cancer

  This study tests a catheter-based method to deliver Gemcitabine straight into or near pancreatic tumors in locally advanced, unresectable cases.

  Recruiting Phase 1/2 Smartwise Sweden AB · Solna · NCT07575191

• Dual-target CAR-T therapy targeting mesothelin and CLDN18.2 for advanced pancreatic cancer

  This treatment will try sequential CAR‑T cell infusions that target mesothelin and CLDN18.2 in people with unresectable or metastatic pancreatic adenocarcinoma who have received prior systemic therapy.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT07066995

• Ablation of unresectable pancreatic cancer with the NanoKnife irreversible electroporation system

  This study will try using the NanoKnife irreversible electroporation device to see if it is safe and can reduce pain and improve quality of life for adults with locally advanced unresectable pancreatic cancer.

  Recruiting Englewood Hospital and Medical Center · Englewood, New Jersey · NCT06937996

• Carbon ion radiotherapy for pancreatic cancer treatment

  This study is testing a new treatment using carbon ion radiotherapy along with two other drugs to see if it can help people with advanced pancreatic cancer live longer and have fewer side effects.

  Recruiting Gansu Wuwei Tumor Hospital · Wuwei, Gansu · NCT06840067

• Using medical cannabis to relieve symptoms in patients with advanced pancreatic cancer

  This study is testing if medical cannabis can help relieve symptoms like pain and nausea in people with advanced pancreatic cancer.

  Recruiting Phase 2 HealthPartners Institute · Saint Louis Park, Minnesota · NCT06605430

• Early detection of pancreatic cancer using exosome-based biomarkers

  This study is testing a new way to find pancreatic cancer early by looking at tiny particles in the blood that carry specific markers.

  Recruiting at 11 sites City of Hope Medical Center · Phoenix, Arizona and 12 other locations · NCT06388967

• Comparing two methods for managing pain in inoperable pancreatic cancer

  This study is testing two different pain management methods for people with inoperable pancreatic cancer to see which one helps them feel better and improves their quality of life.

  Recruiting Chinese University of Hong Kong · Hong Kong, Hong Kong · NCT06160323

• Carbon ion radiotherapy for advanced pancreatic cancer

  This study is testing a new type of radiation treatment called carbon ion therapy to see if it can help people with advanced pancreatic cancer live longer and feel better.

  Recruiting Shanghai Proton and Heavy Ion Center · Shanghai · NCT05424159

• Evaluating tumor types in pancreatic cancer patients receiving FOLFIRINOX treatment

  This study is testing how different types of pancreatic cancer respond to the chemotherapy FOLFIRINOX before surgery to see if it helps make the tumors easier to remove.

  Recruiting Phase 2 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT03977233

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Quick answers

How many Pancreatic Cancer Non-resectable clinical trials are recruiting right now?

13, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (6 trials), China (4 trials), Japan (1 trial), South Korea (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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