Condition

Oral Leukoplakia clinical trials and research

• 6Clinical trials
• 1New in 30 days
• 4Countries

Newest Oral Leukoplakia clinical trials

All recruiting trials (6)

• Salivary IL-8 and Serum IL-6 as Biomarkers to Distinguish Oral Premalignant Disorders in Smokers and Never-Smokers

  This study tests whether salivary IL-8 and blood IL-6 can help tell apart adults with oral premalignant conditions from those with healthy mouths, and whether smoking influences these markers.

  Recruiting British University In Egypt · Cairo · NCT07915570

• Topical and oral metformin to prevent or shrink oral leukoplakia

  This study will test whether using metformin both as a mouth application and as oral tablets can shrink or prevent early oral leukoplakia in adults with mild-to-moderate dysplasia.

  Recruiting Phase 2 Cairo University · Cairo · NCT07387900

• Topical Coenzyme Q10 versus Curcumin for oral leukoplakia treatment

  This trial will test whether applying Coenzyme Q10 or curcumin gels directly to homogeneous oral leukoplakia lesions helps shrink or stabilize them in patients who do not need surgery.

  Recruiting Alexandria University · Alexandria · NCT07331935

• Using Optical Coherence Tomography to Diagnose Oral Cancer

  This study is testing if a special imaging technique called Optical Coherence Tomography can help doctors find oral cancer earlier and more accurately in patients with potentially harmful mouth conditions.

  Recruiting University of Palermo · Palermo · NCT06321003

• Combination treatment of pioglitazone and metformin for high-risk oral lesions

  This study is testing if a combination of two medications, pioglitazone and metformin, can help reduce the size and severity of precancerous oral lesions in patients with oral leukoplakia.

  Recruiting at 2 sites Phase 2 University of Minnesota · Minneapolis, Minnesota and 1 other locations · NCT05727761

• Predicting cancer risk in oral leukoplakia using MAGE-A markers

  This study is trying to see if certain markers in people with oral leukoplakia can help predict their risk of developing oral cancer.

  Recruiting University of Erlangen-Nürnberg Medical School · Erlangen · NCT03975322

Related topics

Quick answers

How many Oral Leukoplakia clinical trials are recruiting right now?

6, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in Egypt (3 trials), United States (1 trial), Italy (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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