Condition
NF1 Mutation clinical trials and research
As of November 12, 2026, Find a Trial lists 3 NF1 Mutation clinical trials that are recruiting, at sites in 5 countries (most in United States (3), Bulgaria (1), Romania (1)). By phase: Phase 1 (2), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 5Countries
Newest NF1 Mutation clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Testing PAS-004 for adults with Neurofibromatosis Type 1 and plexiform neurofibromas | Phase 1 | Birmingham, Alabama and 4 other locations | Recruiting | May 8, 2025 |
| Testing PAS-004 for patients with advanced solid tumors | Phase 1 | San Antonio, Texas and 4 other locations | Recruiting | Mar 8, 2024 |
| T cell receptor depletion for blood cancer treatment | Phase 2 | Minneapolis, Minnesota | Recruiting | Feb 21, 2023 |
All recruiting trials (3)
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Testing PAS-004 for adults with Neurofibromatosis Type 1 and plexiform neurofibromas
This study is testing a new medication called PAS-004 to see if it is safe and helps adults with Neurofibromatosis Type 1 and painful plexiform neurofibromas.
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Testing PAS-004 for patients with advanced solid tumors
This study is testing a new oral medication called PAS-004 to see if it is safe and tolerable for people with advanced solid tumors that have certain genetic mutations.
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T cell receptor depletion for blood cancer treatment
This study is testing a new way to treat blood cancers by using a special treatment before a stem cell transplant to see if it helps both kids and adults do better after the procedure.
Related topics
Quick answers
How many NF1 Mutation clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in United States (3 trials), Bulgaria (1 trial), Romania (1 trial), Australia (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.