Condition
Myeloproliferative Neoplasms clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Myeloproliferative Neoplasms clinical trials that are recruiting, at sites in 11 countries (most in United States (6), Australia (2), Belgium (2)). By phase: Phase 1 (4), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 11Countries
Newest Myeloproliferative Neoplasms clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| INCA036978 for people with myeloproliferative neoplasms | Phase 1 | Birmingham, Alabama and 53 other locations | Recruiting | Mar 2, 2026 |
| MPN PROGRESSion Registry — tracking symptoms, treatments, and disease progression in people with MPNs. | — | Chicago, Illinois and 1 other locations | Recruiting | Jan 23, 2026 |
| INCA035784 for people with CALR‑mutated myeloproliferative neoplasms (myelofibrosis or essential thrombocythemia) | Phase 1 | Phoenix, Arizona and 25 other locations | Recruiting | Jun 6, 2025 |
| Combining Ivosidenib and Ruxolitinib for Advanced Myeloproliferative Neoplasms with IDH1 Mutation | Phase 1 | Chicago, Illinois and 1 other locations | Recruiting | Mar 4, 2024 |
| Evaluating INCA033989 for treating myeloproliferative neoplasms | Phase 1 | Duarte, California and 12 other locations | Recruiting | Sep 13, 2023 |
| Hematopoietic stem cell transplant for blood cancers | Phase 2 | Minneapolis, Minnesota | Recruiting | Oct 19, 2017 |
All recruiting trials (6)
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INCA036978 for people with myeloproliferative neoplasms
This Phase 1 study will test whether INCA036978, given alone or with standard therapy, is safe and tolerable for adults with myeloproliferative neoplasms such as myelofibrosis, polycythemia vera, and essential thrombocythemia.
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MPN PROGRESSion Registry — tracking symptoms, treatments, and disease progression in people with MPNs.
Track long-term symptoms, treatments, and disease progression in adults with myeloproliferative neoplasms to see how these conditions evolve over time.
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INCA035784 for people with CALR‑mutated myeloproliferative neoplasms (myelofibrosis or essential thrombocythemia)
This trial tests whether INCA035784 is safe and tolerable in adults with CALR‑mutated myeloproliferative neoplasms who have already received prior therapies.
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Combining Ivosidenib and Ruxolitinib for Advanced Myeloproliferative Neoplasms with IDH1 Mutation
This study is testing if combining two medications, ivosidenib and ruxolitinib, can help people with advanced myeloproliferative neoplasms that have an IDH1 mutation feel better and improve their treatment outcomes.
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Evaluating INCA033989 for treating myeloproliferative neoplasms
This study is testing a new treatment called INCA033989, alone and with another drug, to see if it’s safe and effective for people with myeloproliferative neoplasms who have certain mutations.
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Hematopoietic stem cell transplant for blood cancers
This study is testing two different ways of doing stem cell transplants for people with blood cancers to see which method works better and is safer.
Related topics
Quick answers
How many Myeloproliferative Neoplasms clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in United States (6 trials), Australia (2 trials), Belgium (2 trials), Germany (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 4, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.