Condition
Multiple Sclerosis, Secondary Progressive clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Multiple Sclerosis, Secondary Progressive clinical trials that are recruiting, at sites in 3 countries (most in United States (4), Poland (1), Switzerland (1)). By phase: Phase 1 (1), Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 3Countries
Newest Multiple Sclerosis, Secondary Progressive clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Observational study of patients with Multiple Sclerosis in Switzerland | — | Basel | Recruiting | Jul 29, 2024 |
| Brief low-oxygen breathing to boost nerve plasticity and arm strength in MS | — | Chicago, Illinois | Recruiting | Apr 30, 2024 |
| Breathing low oxygen levels to improve strength in people with multiple sclerosis | — | Chicago, Illinois | Recruiting | Feb 26, 2024 |
| Anti-CD19 CAR-T for non-relapsing progressive multiple sclerosis | Phase 1 | Palo Alto, California | Recruiting | Nov 18, 2023 |
| Cladribine treatment for non-active progressive multiple sclerosis | Phase 2/3 | Warsaw, Masovian Voivodeship | Recruiting | Jul 27, 2023 |
| Investigating risk factors for disability progression in Multiple Sclerosis | — | Los Angeles, California | Recruiting | Jan 24, 2022 |
All recruiting trials (6)
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Observational study of patients with Multiple Sclerosis in Switzerland
This study is trying to find out more about the early signs of Multiple Sclerosis and how it changes over time by looking at health data from patients in Switzerland.
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Brief low-oxygen breathing to boost nerve plasticity and arm strength in MS
This will see if brief bouts of low-oxygen breathing (acute intermittent hypoxia) can quickly improve arm and hand strength and nerve signaling in people with relapsing-remitting MS who have arm weakness.
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Breathing low oxygen levels to improve strength in people with multiple sclerosis
This study is testing if short periods of low oxygen can help people with multiple sclerosis get stronger and improve their brain's ability to control movement.
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Anti-CD19 CAR-T for non-relapsing progressive multiple sclerosis
This Phase 1 trial will test whether a single infusion of KYV-101 (anti-CD19 CAR-T cells) is safe and can slow worsening in adults with non-relapsing progressive MS.
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Cladribine treatment for non-active progressive multiple sclerosis
This study is testing whether a new treatment called cladribine can help people with non-active progressive multiple sclerosis feel better and slow down their disease.
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Investigating risk factors for disability progression in Multiple Sclerosis
This study is trying to find out what factors might make disability get worse in people with Multiple Sclerosis by looking at their medical history and MRI scans.
Related topics
Quick answers
How many Multiple Sclerosis, Secondary Progressive clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (4 trials), Poland (1 trial), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.