Condition
Multiple Sclerosis (MS) Secondary Progressive clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Multiple Sclerosis (MS) Secondary Progressive clinical trials that are recruiting, at sites in 3 countries (most in United States (3), China (1), Israel (1)). By phase: Phase 1 (2), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 3Countries
Newest Multiple Sclerosis (MS) Secondary Progressive clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Safety and dosing of S103 cells in progressive or refractory multiple sclerosis | Phase 1 | Xi'an, Shaanxi | Recruiting | May 14, 2026 |
| TRX319 treatment for people with primary or secondary progressive multiple sclerosis | Phase 1/2 | La Jolla, California and 7 other locations | Recruiting | Mar 17, 2026 |
| Home-based functional balance program for people with multiple sclerosis | — | Chicago, Illinois | Recruiting | Jan 21, 2026 |
| Using short selfie videos to measure walking and speech changes in people with MS | — | San Francisco, California | Recruiting | Oct 30, 2025 |
| HBI0101 CAR-T for refractory B‑cell autoimmune rheumatic diseases | Phase 1 | Jerusalem | Recruiting | Jul 25, 2025 |
All recruiting trials (5)
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Safety and dosing of S103 cells in progressive or refractory multiple sclerosis
This trial tests S103 BCMA-CAR T cells in adults with progressive or refractory MS to see if it can be safely given and hint at benefit.
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TRX319 treatment for people with primary or secondary progressive multiple sclerosis
This trial will test whether the experimental therapy TRX319, given with or without a short bendamustine pre-conditioning, is safe and can slow or improve disability in adults with primary or secondary progressive MS.
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Home-based functional balance program for people with multiple sclerosis
This project will test whether a home-based functional balance program helps adults with multiple sclerosis improve physical and cognitive function and daily activities.
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Using short selfie videos to measure walking and speech changes in people with MS
This project will test whether short selfie videos taken by people with MS can reliably show walking and speech changes similar to what clinicians see in person.
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HBI0101 CAR-T for refractory B‑cell autoimmune rheumatic diseases
This will test a single infusion of HBI0101 CAR‑T cells in adults with severe, treatment‑resistant B‑cell autoimmune diseases such as SLE, systemic sclerosis, idiopathic inflammatory myopathy, rheumatoid arthritis, or primary progressive MS.
Related topics
Quick answers
How many Multiple Sclerosis (MS) Secondary Progressive clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (3 trials), China (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.