Condition

MPNST clinical trials and research

• 4Clinical trials
• 1Country

Newest MPNST clinical trials

All recruiting trials (4)

• Safety and preliminary activity of BMS-986504 in unresectable MPNST

  A new medicine called BMS-986504 is being tested to see if it is safe and may help people with unresectable malignant peripheral nerve sheath tumors, especially those whose tumors lack MTAP.

  Recruiting Phase 1/2 Case Comprehensive Cancer Center · Cleveland, Ohio · NCT07549022

• Handheld mass spectrometry to tell MPNST, neurofibroma, and normal nerve tissue during surgery

  This study will test whether a handheld mass spectrometry device can quickly tell malignant peripheral nerve sheath tumors (MPNST) from neurofibromas and normal nerve tissue during surgery for patients having tumor removal.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT07298083

• Testing selinexor for treating Wilms tumors and other solid tumors

  This study is testing if selinexor can help children with certain hard-to-treat tumors, like Wilms tumors, feel better and improve their health.

  Recruiting at 16 sites Phase 2 Memorial Sloan Kettering Cancer Center · Los Angeles, California and 15 other locations · NCT05985161

• Selumetinib plus ZEN-3694 with durvalumab for certain sarcomas and NF1-associated MPNST

  This trial tests a combination of medicines to see if they can help adults with unresectable or metastatic sarcomas, including NF1-associated MPNST.

  Recruiting Phase 2 University of Alabama at Birmingham · Birmingham, Alabama · NCT05253131

Related topics

Quick answers

How many MPNST clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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