Condition

Lower Extremity Fracture clinical trials and research

• 5Clinical trials
• 2Countries

Newest Lower Extremity Fracture clinical trials

All recruiting trials (5)

• Sedation and pain control for adults with fractures and dislocations in the emergency department

  This project will try different sedation and pain-control methods to see which gives adults the best pain relief and satisfaction during emergency-room reductions of fractures or dislocations.

  Recruiting at 3 sites Region Zealand · Holbæk, Region Sjælland and 2 other locations · NCT07314450

• Nerve blocks before surgery for older adults with lower leg fractures

  This will test whether giving a peripheral nerve-block injection before surgery helps people aged 50 and older with lower leg fractures recover with fewer complications and less opioid use.

  Recruiting Phase 4 University of Maryland, Baltimore · Baltimore, Maryland · NCT07217626

• Blood flow restriction–enhanced rehabilitation for people with tibial shaft fractures.

  This trial will test whether using a blood flow restriction device during low-load strengthening exercises helps adults with tibial shaft fractures regain muscle strength and size, heal their fracture, and return to normal function faster than standard exercises alone.

  Recruiting Denver Health and Hospital Authority · Denver, Colorado · NCT06496035

• Comparing oral and intravenous antibiotics for treating infected nonunion of fractures

  This study is testing whether taking antibiotics by mouth works as well as getting them through an IV for people with infected fractures that haven't healed properly after surgery.

  Recruiting at 9 sites Phase 3 Major Extremity Trauma Research Consortium · Indianapolis, Indiana and 12 other locations · NCT05699174

• Breathing exercises before joint surgery

  This study is testing if breathing exercises before joint surgery can help patients breathe better after their operation and avoid complications.

  Recruiting University of Florida · Jacksonville, Florida · NCT05381818

Related topics

Quick answers

How many Lower Extremity Fracture clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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