Sedation and pain control for adults with fractures and dislocations in the emergency department

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study follows adults with upper or lower extremity fractures or joint dislocations who need painful reduction or casting in the emergency department. Patients receive the routine sedation or analgesia selected by their clinicians, such as systemic procedural sedation, regional nerve or hematoma blocks, or no analgesia, and outcomes are recorded. The study compares patient-reported pain relief and satisfaction, clinician satisfaction, and the occurrence of adverse events across these approaches. Data are collected at three Danish emergency departments to provide real-world evidence on which methods work best in routine care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥18.
2. Patients with the following injuries are eligible:

   1. Reduction treatment of shoulder dislocation
   2. Reduction treatment of elbow dislocation
   3. Reduction treatment of distal radius fractures, application of cast
   4. Reduction treatment of finger fractures/dislocation
   5. Casting treatment of upper extremity fractures

      * Proximal humerus fracture, application of fixed sling
      * Humeral shaft fracture, application of Sarmiento brace
      * Supracondylar fracture, application of angled cast
   6. Reduction treatment of hip dislocation
   7. Reduction treatment of patella dislocation
   8. Reduction of tibial shaft fracture, application of cast
   9. Reduction treatment of ankle fractures including distal tibia fracture
   10. Reduction treatment for toe fractures/dislocation
   11. Casting treatment of lower extremity fractures

       * Distal femur fracture, application of cast/traction
       * Proximal tibia fracture, application of cast or hinged brace
       * Ankle fracture, application of walker

Exclusion Criteria:

1. Unable to give informed consent (e.g. unconscious, psychotic or dementia)
2. Unwilling to participate in the study
3. Prior inclusion in the study
4. Already included in another clinical study at the same day/hospital visit
5. Pregnant or breastfeeding

Where it's running

• Emergency Department, Holbæk Hospital
  Holbæk, Region Sjælland, Denmark Recruiting
• Emergency Department, Zealand University Hospital
  Køge, Region Sjælland, Denmark Recruiting
• Emergency Department, Odense University Hospital
  Odense, Region Syddanmark, Denmark Recruiting

Study contacts

• Study coordinator: Sophie Sværke, MD
• Email: Ibes@regionsjaelland.dk
• Phone: 31368854

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.