Condition

Homologous Recombination Deficiency clinical trials and research

• 7Clinical trials
• 5Countries

Newest Homologous Recombination Deficiency clinical trials

All recruiting trials (7)

• Lorigerlimab in pancreatic cancer with BRCA/RAD51 gene mutations

  This phase 2 study tests Lorigerlimab in adults with metastatic pancreatic cancer who have BRCA1/2, PALB2, RAD51C, or RAD51D germline mutations.

  Recruiting Phase 2 University of Miami · Miami, Florida · NCT07565155

• Oral treatment with MOMA-313 for advanced solid tumors

  This study is testing a new oral treatment called MOMA-313 for people with advanced solid tumors that can't be cured, to see how safe it is and how well it works, especially for those with certain genetic changes.

  Recruiting at 14 sites Phase 1 MOMA Therapeutics · Goodyear, Arizona and 17 other locations · NCT06545942

• Testing EIS-12656 for advanced solid tumors

  This study is testing a new drug called EIS-12656 to see if it can safely help people with advanced solid tumors that have certain genetic mutations.

  Recruiting at 4 sites Phase 1/2 Eisbach Bio GmbH · Shreveport, Louisiana and 3 other locations · NCT06525298

• Cisplatin treatment for pancreatic cancer patients with specific genetic deficiencies

  This study is testing if a chemotherapy drug called cisplatin can help people with advanced pancreatic cancer who have specific genetic issues after their first treatment didn't work.

  Recruiting Phase 2/3 Fudan University · Shanghai · NCT06095141

• Using Olaparib for Patients with Malignant Mesothelioma and Genetic Mutations

  This study is testing if the drug olaparib can help people with malignant mesothelioma who have certain genetic mutations by seeing if it can shrink their tumors.

  Recruiting Phase 2 University of Chicago · Chicago, Illinois · NCT04515836

• Treatment of advanced cancers with AMXI-5001

  This study is testing a new oral medication called AMXI-5001 to see if it can help adults with advanced cancers that haven't responded to other treatments.

  Recruiting at 4 sites Phase 1/2 AtlasMedx, Incorporated · Los Angeles, California and 3 other locations · NCT04503265

• Combining Bipolar Androgen Therapy with Carboplatin for Advanced Prostate Cancer

  This study is testing if combining a new hormone treatment with a chemotherapy drug can help men with advanced prostate cancer that hasn't responded to other treatments.

  Recruiting Phase 2 St Vincent's Hospital, Sydney · Sydney, New South Wales · NCT03522064

Related topics

Quick answers

How many Homologous Recombination Deficiency clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (5 trials), Spain (1 trial), United Kingdom (1 trial), China (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 2, Phase 1: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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