Condition

High Grade Serous Ovarian Cancer clinical trials and research

• 11Clinical trials
• 1New in 30 days
• 13Countries

Newest High Grade Serous Ovarian Cancer clinical trials

All recruiting trials (11)

• FRα expression in high-grade serous ovarian cancer (FRα positive)

  A retrospective study in Greece will test how often Folate Receptor Alpha is present in tumor samples from adults diagnosed with high-grade serous ovarian cancer.

  Recruiting Hellenic Cooperative Oncology Group · Athens · NCT07889843

• Routine shallow-coverage Whole Genome Sequencing of Cervical Smears to See if Ovarian Cancer is Found Earlier

  Researchers test whether analyzing DNA from cervical smears with shallow whole-genome sequencing can help detect high-grade serous ovarian cancer early in patients undergoing treatment for this cancer.

  Recruiting Institut Claudius Regaud · Toulouse · NCT07821879

• IDE034 for adults with advanced solid tumors that express B7-H3 and PTK7

  This trial will test IDE034 to see if it is safe and works in adults with advanced or metastatic solid tumors that express B7-H3 and PTK7.

  Recruiting at 26 sites Phase 1 IDEAYA Biosciences · Duarte, California and 25 other locations · NCT07503808

• Idetrexed plus olaparib for high-grade serous ovarian cancer

  This trial tests whether combining idetrexed and olaparib helps people with high-grade serous ovarian cancer that is resistant to standard treatments.

  Recruiting Phase 1 Institute of Cancer Research, United Kingdom · Cambridge, Cambridgeshire and 2 other locations · NCT06976892

• Investigating the Role of RPL8 Protein in Ovarian Cancer

  This study is trying to see if the RPL8 protein in ovarian cancer tumors can help doctors understand the disease better and make more informed treatment choices for patients.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT06777082

• Exploring Tumor Biology in Ovarian Cancer with Advanced Imaging Techniques

  This study is testing new imaging techniques to better understand ovarian cancer tumors and improve personalized treatment for patients.

  Recruiting Institut du Cancer de Montpellier - Val d'Aurelle · Montpellier · NCT06084195

• Testing Rinatabart Sesutecan for advanced solid tumors

  This study is testing a new drug called Rinatabart Sesutecan to see if it can safely help people with advanced solid tumors, like certain types of ovarian and endometrial cancers.

  Recruiting at 67 sites Phase 1/2 Genmab · Phoenix, Arizona and 66 other locations · NCT05579366

• Testing a new drug combination for certain types of gynecological cancers

  This study is testing a new combination of two drugs to see if they can help people with certain types of gynecological cancers feel better and improve their treatment outcomes.

  Recruiting at 4 sites Phase 2 University of Oklahoma · Orlando, Florida and 3 other locations · NCT05512208

• Evaluating Olvi-Vec with chemotherapy for advanced ovarian cancer

  This study is testing if a new virus-based treatment called Olvi-Vec, combined with chemotherapy, can help women with tough-to-treat advanced ovarian cancer live longer and feel better.

  Recruiting at 33 sites Phase 3 Genelux Corporation · Mobile, Alabama and 32 other locations · NCT05281471

• Using ctDNA to Measure Treatment Effectiveness in Ovarian Cancer

  This study is testing if measuring tumor DNA in the blood can help predict how well treatment works for people with high-grade serous ovarian cancer who are on maintenance therapy after chemotherapy.

  Recruiting Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai · NCT05027828

• Assessing the safety and effects of Azirkitug in cancer patients

  This study is testing a new cancer drug called Azirkitug to see how safe it is and how well it works for adults with certain types of lung and head and neck cancers.

  Recruiting at 47 sites Phase 1 AbbVie · Duarte, California and 47 other locations · NCT05005403

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Quick answers

How many High Grade Serous Ovarian Cancer clinical trials are recruiting right now?

11, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (5 trials), China (2 trials), Japan (2 trials), South Korea (2 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 1/2: 1, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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