Condition

Fuchs' Endothelial Dystrophy clinical trials and research

• 10Clinical trials
• 7Countries

Newest Fuchs' Endothelial Dystrophy clinical trials

All recruiting trials (10)

• EO2002 therapy for corneal edema due to endothelial dysfunction

  This trial tests whether a single intracameral injection of EO2002 cells can improve vision and reduce corneal thickness in adults with corneal edema from endothelial dysfunction.

  Recruiting Phase 2 Emmecell · Torrance, California and 9 other locations · NCT07729137

• PVEK corneal implant to treat corneal swelling

  This study will test a PVEK tissue‑engineered corneal implant to see if it is safe and helps people with corneal swelling from Fuchs' endothelial dystrophy or pseudophakic bullous keratopathy who need endothelial keratoplasty.

  Recruiting Phase 1 Precise Bio · Yerevan and 2 other locations · NCT07325097

• Understanding Fuchs' Endothelial Corneal Dystrophy and its Genetic Links

  This study is trying to understand how Fuchs' Endothelial Corneal Dystrophy affects younger people with a genetic link to the condition by using advanced imaging to track changes over time.

  Recruiting University College, London · London · NCT06881771

• Using plasma rich in growth factors during corneal transplants

  This study tests if using plasma rich in growth factors during corneal transplants can help patients keep more healthy cells after surgery compared to standard methods.

  Recruiting at 2 sites University of Miami · Miami, Florida and 1 other locations · NCT06261346

• Effects of Ripasudil on Patients with Fuchs' Endothelial Dystrophy Undergoing Cataract Surgery

  This study is testing if a new eye drop called ripasudil can help people with Fuchs' Endothelial Dystrophy have better results after cataract surgery.

  Recruiting Phase 3 Singapore Eye Research Institute · Singapore, Singapore · NCT06048380

• OPTIMISE — safer steroid plans after DMEK cornea transplant

  This study tests whether using a milder steroid eye drop plan or stopping steroids earlier after DMEK can still prevent graft rejection while reducing the risk of high eye pressure in adults receiving corneal transplants.

  Recruiting at 6 sites Phase 4 Maastricht University Medical Center · Apeldoorn, Gelderland and 7 other locations · NCT05716945

• Assessing the safety of EO2002 injections for corneal conditions

  This study is testing if EO2002 injections are safe for people with corneal conditions like Fuchs' dystrophy or pseudophakic bullous keratopathy.

  Recruiting Phase 1 Asociación para Evitar la Ceguera en México · Mexico City, Mexico City · NCT05636579

• Tissue-engineered endothelial keratoplasty with lab-grown corneal endothelial grafts

  This trial will test whether a graft made from lab-grown human corneal endothelial cells can safely restore vision in adults with mild to moderate corneal endothelial failure such as Fuchs' dystrophy or bullous keratopathy.

  Recruiting Phase 1 Singapore Eye Research Institute · Singapore · NCT04319848

• Using Glanatec® to treat Fuchs' Endothelial Dystrophy

  This study is testing if Glanatec®, a glaucoma medication, can help clear corneal cells in people with Fuchs' Endothelial Dystrophy who have had a specific eye surgery.

  Recruiting Phase 4 Endeavor Health · Glenview, Illinois · NCT03249337

• Testing Brillouin Microscopy for Diagnosing Corneal Conditions

  This study is testing a new imaging technique called Brillouin microscopy to see if it can better diagnose corneal issues like keratoconus and ectasia in people.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT02118922

Related topics

Quick answers

How many Fuchs' Endothelial Dystrophy clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (4 trials), Singapore (2 trials), Mexico (1 trial), United Kingdom (1 trial), Armenia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 4: 2, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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