Condition

Exocrine Pancreatic Insufficiency (EPI) clinical trials and research

• 5Clinical trials
• 9Countries

Newest Exocrine Pancreatic Insufficiency (EPI) clinical trials

All recruiting trials (5)

• Microbial pancreatic enzyme therapy versus porcine enzyme in chronic pancreatitis with exocrine pancreatic insufficiency

  This study tests whether a microbial (fungal) pancreatic enzyme product can work as well as the standard porcine enzyme in adults with chronic pancreatitis and PEI.

  Recruiting Phase 3 Asian Institute of Gastroenterology, India · Hyderabad, Telangana · NCT07697352

• New lipase NHS7108 safety and potential efficacy in adults with exocrine pancreatic insufficiency

  A 2-period study tests whether the new lipase NHS7108 works safely for adults with EPI by comparing it to the standard pancrelipase (Zenpep) at several doses over 14 days each.

  Recruiting at 7 sites Phase 2 Société des Produits Nestlé (SPN) · Scottsdale, Arizona and 38 other locations · NCT07559175

• Detecting pancreatic dysfunction in adults with type 2 diabetes

  This project tests whether blood tests, a stool sample, and an ultrasound can identify pancreatogenic diabetes in adults with type 2 diabetes.

  Recruiting West Kazakhstan Marat Ospanov Medical University · Aktobe, Aktobe · NCT07512934

• ANG003 for pancreatic enzyme replacement in cystic fibrosis–related exocrine pancreatic insufficiency

  This trial will test whether ANG003, a new pancreatic enzyme replacement, works as well as Creon for people with cystic fibrosis who have exocrine pancreatic insufficiency.

  Recruiting at 21 sites Phase 2 Anagram Therapeutics, Inc. · Long Beach, California and 27 other locations · NCT07450547

• Evaluating RELiZORB for managing pancreatic enzyme insufficiency in tube-fed patients

  This study is testing if RELiZORB can help tube-fed patients with pancreatic enzyme insufficiency digest food better while they are in the hospital.

  Recruiting Phase 3 Massachusetts General Hospital · Boston, Massachusetts · NCT06691893

Related topics

Quick answers

How many Exocrine Pancreatic Insufficiency (EPI) clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (3 trials), Bulgaria (1 trial), Hungary (1 trial), Italy (1 trial), Poland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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