Condition
Clear Cell Renal Cell Carcinoma (ccRCC) clinical trials and research
Research outlook What's coming for Kidney cancer: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 8 Clear Cell Renal Cell Carcinoma (ccRCC) clinical trials that are recruiting, at sites in 15 countries (most in United States (6), France (2), Germany (2)). By phase: Phase 1/2 (3), Phase 1 (2), Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 8Clinical trials
- 15Countries
Newest Clear Cell Renal Cell Carcinoma (ccRCC) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| REGN15505 Alone or With Cemiplimab or REGN4336 in Advanced Prostate Cancer and Kidney Cancer | Phase 1/2 | Goodyear, Arizona and 5 other locations | Recruiting | May 18, 2026 |
| Pucotenlimab plus vorolanib before surgery for clear cell kidney cancer | Phase 2 | Guangzhou, Other (Non U.s.) | Recruiting | Feb 4, 2026 |
| First-line immune-checkpoint antibody combinations for advanced clear cell kidney cancer | Phase 2 | Washington D.C., District of Columbia and 4 other locations | Recruiting | Sep 23, 2025 |
| Using 18F-Labeled NY104 for PET/CT Imaging in Renal Cell Carcinoma | — | Qingdao, Shandong | Recruiting | Apr 8, 2025 |
| Testing a new drug for advanced solid tumors | Phase 1/2 | Los Angeles, California and 10 other locations | Recruiting | May 14, 2024 |
| Testing KO-2806 for advanced solid tumors | Phase 1 | Phoenix, Arizona and 37 other locations | Recruiting | Sep 7, 2023 |
| Zanzalintinib with immune checkpoint drugs for advanced solid tumors | Phase 1 | Phoenix, Arizona and 121 other locations | Recruiting | Jan 4, 2022 |
| Evaluating the safety and effectiveness of REGN5678 alone or with cemiplimab for advanced prostate and kidney cancer | Phase 1/2 | Gilbert, Arizona and 26 other locations | Recruiting | Jun 3, 2019 |
All recruiting trials (8)
-
REGN15505 Alone or With Cemiplimab or REGN4336 in Advanced Prostate Cancer and Kidney Cancer
This trial tests REGN15505 by itself or with cemiplimab or REGN4336 to see if it helps adults with metastatic castration-resistant prostate cancer or clear cell renal cell carcinoma.
-
Pucotenlimab plus vorolanib before surgery for clear cell kidney cancer
This trial tests whether giving pucotenlimab with vorolanib before surgery can shrink localized clear cell kidney tumors and make kidney-sparing surgery easier for adults with difficult-to-remove tumors.
-
First-line immune-checkpoint antibody combinations for advanced clear cell kidney cancer
This trial tests whether combining fianlimab and cemiplimab, with or without ipilimumab, works better than the standard ipilimumab plus nivolumab as first treatment for people with advanced clear cell kidney cancer.
-
Using 18F-Labeled NY104 for PET/CT Imaging in Renal Cell Carcinoma
This study is testing a new imaging method using a special dye to see if it can help doctors better diagnose kidney cancer and understand how a low-dose medication affects the images in patients.
-
Testing a new drug for advanced solid tumors
This study is testing a new drug called REGN10597 to see if it is safe and effective for adults with advanced solid tumors like melanoma and kidney cancer.
-
Testing KO-2806 for advanced solid tumors
This study is testing a new treatment called KO-2806 for adults with advanced solid tumors that have certain genetic changes to see if it can help them feel better.
-
Zanzalintinib with immune checkpoint drugs for advanced solid tumors
This trial will test whether zanzalintinib alone or combined with immune drugs (nivolumab, with or without ipilimumab or relatlimab) is safe and helps people with advanced or metastatic solid tumors such as renal cell, prostate, urothelial, and liver cancers.
-
Evaluating the safety and effectiveness of REGN5678 alone or with cemiplimab for advanced prostate and kidney cancer
This study is testing if a new drug called REGN5678, alone or with another drug called cemiplimab, can safely shrink tumors in adults with advanced prostate and kidney cancer.
Related topics
Quick answers
How many Clear Cell Renal Cell Carcinoma (ccRCC) clinical trials are recruiting right now?
8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 15 countries. The most sites are in United States (6 trials), France (2 trials), Germany (2 trials), Italy (2 trials), Spain (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 3, Phase 1: 2, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.