Condition

Carcinoma, Non-Small-Cell Lung (NSCLC) clinical trials and research

• 8Clinical trials
• 1New in 30 days
• 34Countries

Newest Carcinoma, Non-Small-Cell Lung (NSCLC) clinical trials

All recruiting trials (8)

• PF-08098488 in adults with advanced solid tumors

  This study tests PF-08098488 in adults whose cancer has progressed or returned after prior treatment.

  Recruiting at 4 sites Phase 1 Pfizer · Grand Rapids, Michigan and 3 other locations · NCT07903415

• Neoadjuvant Cryo-Thermal Ablation with Toripalimab and Chemo for Resectable NSCLC

  This study tests whether using Cryo-Thermal Ablation before chemo-immunotherapy helps people with resectable NSCLC see better outcomes.

  Recruiting Phase 2 West China Hospital · Chengdu, Sichuan and 8 other locations · NCT07855965

• Vortioxetine for cognitive problems in ALK/ROS1-positive NSCLC treated with lorlatinib

  This observational study tests whether vortioxetine can help with cognitive and neurological side effects in adults with ALK/ROS1-positive NSCLC who are taking lorlatinib.

  Recruiting Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo · Bogotá · NCT07633626

• PF-08634404 Alone or with chemotherapy in early-stage or locally advanced NSCLC

  This study tests PF-08634404 by itself or with chemotherapy in adults with early-stage or locally advanced non-small cell lung cancer that may be surgically removable or were candidates for additional therapy after initial treatment.

  Recruiting at 28 sites Phase 2 Pfizer · Huntsville, Alabama and 36 other locations · NCT07489066

• PF-08634404 plus chemotherapy versus pembrolizumab-based chemotherapy for advanced non-small cell lung cancer

  This will test whether PF-08634404 combined with chemotherapy works better than pembrolizumab plus chemotherapy for adults with locally advanced or metastatic non-small cell lung cancer who have not received prior treatment for their advanced disease.

  Recruiting at 464 sites Phase 3 Pfizer · Bullhead City, Arizona and 483 other locations · NCT07222566

• Radiotherapy to the primary lung tumor in metastatic NSCLC

  This trial tests whether adding radiotherapy to the primary lung tumor, alongside standard drug therapy, helps people with metastatic non-small cell lung cancer live longer and feel better.

  Recruiting Phase 3 Trans Tasman Radiation Oncology Group · Blacktown, New South Wales and 5 other locations · NCT07135882

• Evaluating PET scans for predicting treatment response in lung cancer patients

  This study is testing if PET scans can help predict how well lung cancer patients will respond to immunotherapy, with or without chemotherapy.

  Recruiting Centre Antoine Lacassagne · Nice · NCT06833229

• Combining Sigvotatug Vedotin and Pembrolizumab for Non-Small Cell Lung Cancer

  This study is testing a new combination of two treatments, Sigvotatug Vedotin and pembrolizumab, to see if it helps people with advanced non-small cell lung cancer feel better compared to just using pembrolizumab alone.

  Recruiting at 355 sites Phase 3 Pfizer · Fullerton, California and 388 other locations · NCT06758401

Related topics

Quick answers

How many Carcinoma, Non-Small-Cell Lung (NSCLC) clinical trials are recruiting right now?

8, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 34 countries. The most sites are in United States (4 trials), China (4 trials), Australia (4 trials), France (3 trials), Germany (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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