Comparing Botox injections to conservative management for female sexual function in bladder pain syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effects of intradetrusor onabotulinumtoxinA injections compared to conservative management on female sexual function in patients diagnosed with bladder pain syndrome. The study focuses on women aged 18 and older who experience significant bladder pain and associated sexual dysfunction. Participants will be evaluated based on their O'Leary Sant scores to determine eligibility, and the study aims to assess the impact of these interventions on quality of life and sexual health. The research is conducted at the Walter Reed National Military Medical Center.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female 18 years of age and older
* For bladder pain syndrome participants: O'Leary Sant score 13 or greater
* For healthy controls: O'Leary Sant score 12 or less
* DEERS eligible (care provided by military health care system)

Exclusion Criteria:

* Contraindications for bladder Botox
* Current use of alternative treatment for bladder pain syndrome
* Neurogenic bladder
* Other urinary tract disease
* Pelvic organ prolapse stage 3 or greater
* Pregnancy or breastfeeding
* Non-English speakers

Where it's running

• Walter Reed National Military Medical Center
  Bethesda, Maryland, United States Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.