Condition

Acute Leukemia of Ambiguous Lineage clinical trials and research

• 11Clinical trials
• 13Countries

Newest Acute Leukemia of Ambiguous Lineage clinical trials

All recruiting trials (11)

• Choosing the Right Treatment Intensity for Adults with Acute Myeloid Leukemia and Myeloid Neoplasms

  This study tests whether a computer-guided randomization can help decide if a patient should receive higher- or lower-intensity chemotherapy when they’re not clearly fit, to see which approach is more helpful for adults with AML or related myeloid cancers.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07094750

• FLAG‑Ida chemotherapy followed by reduced‑intensity total‑body irradiation and donor stem cell transplant for adults 60+ with adverse‑risk AML or other high‑grade myeloid cancers

  This trial tests whether FLAG‑Ida chemotherapy given immediately before lower‑intensity total‑body radiation and a donor stem cell transplant can improve outcomes for adults 60 and older with newly diagnosed adverse‑risk acute myeloid leukemia or similar high‑grade myeloid cancers.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07046078

• Using revumenib to treat acute leukemia after stem cell transplant

  This study is testing a new drug called revumenib to see if it can help people with acute leukemia feel better after they’ve had a stem cell transplant.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06575296

• Restoring gut bacteria before stem cell transplant for blood cancer patients

  This study is testing if restoring gut bacteria with a special treatment before stem cell transplants can help blood cancer patients have better health and treatment outcomes.

  Recruiting at 6 sites Phase 2 Imperial College London · Birmingham, England and 7 other locations · NCT06355583

• Combining venetoclax and blinatumomab with standard chemotherapy for infants with acute leukemia

  This study is testing whether adding two new treatments, venetoclax and blinatumomab, to standard chemotherapy can help infants with acute leukemia do better and stay cancer-free longer.

  Recruiting at 117 sites Phase 2 National Cancer Institute (NCI) · Birmingham, Alabama and 116 other locations · NCT06317662

• Combining revumenib, azacitidine, and venetoclax for treating pediatric and young adult patients with tough cases of acute myeloid leukemia

  This study is testing a new combination of drugs to see if it can help young patients with tough cases of acute myeloid leukemia feel better and achieve remission.

  Recruiting at 10 sites Phase 1 St. Jude Children's Research Hospital · San Diego, California and 9 other locations · NCT06177067

• Using cord blood transplant and chemotherapy to treat high-risk blood cancers

  This study is testing if combining umbilical cord blood transplants with certain chemotherapy treatments can help people with high-risk blood cancers do better and have fewer side effects.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06013423

• Combining Venetoclax and Azacitidine for treating Acute Leukemia of Ambiguous Lineage

  This study is testing if combining two medications, venetoclax and azacitidine, can help people aged 15 to 65 who have just been diagnosed with Acute Leukemia of Ambiguous Lineage feel better and live longer.

  Recruiting Phase 2 The First Affiliated Hospital of Soochow University · Suzhou · NCT05901974

• Venetoclax treatment for high-risk blood cancers in young patients

  This study is testing a new combination of a drug called venetoclax with chemotherapy to see if it helps young patients with high-risk blood cancers feel better while keeping side effects low.

  Recruiting at 5 sites Phase 1 Dana-Farber Cancer Institute · San Francisco, California and 4 other locations · NCT05292664

• ALL-style chemotherapy for people with acute leukemia of ambiguous lineage.

  This trial will try ALL-style chemotherapy (including vincristine, daunorubicin, cyclophosphamide, L-asparaginase, and prednisone) in people aged 14 and older with acute leukemia of ambiguous lineage and may offer stem-cell transplant after remission.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality · NCT04440267

• Revumenib treatment for relapsed/refractory leukemias with specific genetic mutations

  This study is testing a new drug called revumenib to see if it can help people with certain types of relapsed or hard-to-treat leukemias that have specific genetic changes.

  Recruiting at 38 sites Phase 1/2 Syndax Pharmaceuticals · Duarte, California and 56 other locations · NCT04065399

Related topics

Quick answers

How many Acute Leukemia of Ambiguous Lineage clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (8 trials), China (2 trials), Puerto Rico (2 trials), Australia (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1: 3, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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