Condition

ACL - Anterior Cruciate Ligament Rupture clinical trials and research

• 7Clinical trials
• 7Countries

Newest ACL - Anterior Cruciate Ligament Rupture clinical trials

All recruiting trials (7)

• Strength training with blood-flow restriction after ACL reconstruction

  This trial will test whether adding blood flow restriction to light strength training helps people recovering from ACL reconstruction regain muscle, strength, and knee function during outpatient rehabilitation.

  Recruiting University Hospital, Bonn · Bonn, North Rhine-Westphalia · NCT07043569

• Conventional rehabilitation with or without digital therapy to restore quadriceps activation after ACL reconstruction

  This trial tests whether adding a smartphone-based digital therapy to standard physiotherapy helps adults recovering from ACL reconstruction overcome quadriceps muscle inhibition.

  Recruiting GCS Ramsay Santé pour l'Enseignement et la Recherche · Lyon, France · NCT07030764

• Microbial Profile of the Knee Joint During ACL Surgery

  This study tests whether advanced DNA sequencing can detect hidden knee infections or microbiome changes in people undergoing ACL reconstruction or ACL revision surgery.

  Recruiting GCS Ramsay Santé pour l'Enseignement et la Recherche · Lyon · NCT07009392

• Exercise with blood flow restriction for patients with complete ACL tears

  This study is testing if exercising with blood flow restriction can help people with complete ACL tears recover better than just standard treatment alone.

  Recruiting at 2 sites European University Cyprus · Nicosia and 1 other locations · NCT06727344

• Assessing soleus muscle strength in patients with ACL tears

  This study is testing the strength of a muscle in the calf of people with ACL tears to see how it compares to their uninjured leg and to healthy volunteers.

  Recruiting University of Liverpool · Liverpool · NCT06235736

• Optimizing graft selection for ACL reconstruction

  This study is testing which type of graft—quadriceps tendon, hamstring tendons, or patellar tendon—works best for helping young adults recover from their first ACL injury.

  Recruiting Hvidovre University Hospital · Hvidovre · NCT05342441

• Comparing quadriceps tendon and hamstring autografts for ACL reconstruction in young patients

  This study is testing whether using quadriceps tendon grafts instead of hamstring grafts for ACL surgery can lead to better recovery for young patients aged 10-18.

  Recruiting at 6 sites McMaster University · Hamilton, Ontario and 5 other locations · NCT03896464

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Quick answers

How many ACL - Anterior Cruciate Ligament Rupture clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in France (2 trials), United Kingdom (1 trial), Canada (1 trial), Japan (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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