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ACL clinical trials and research
As of November 12, 2026, Find a Trial lists 7 ACL clinical trials that are recruiting, at sites in 4 countries (most in Italy (3), United States (2), United Kingdom (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 4Countries
Newest ACL clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Ways to Boost Quadriceps Power After ACL Surgery | — | Madison, Wisconsin | Recruiting | Jun 30, 2026 |
| ACL reconstruction with the over-the-top technique plus lateral extra-articular tenodesis in older versus younger patients | — | Bologna, Bologna | Recruiting | Jun 27, 2025 |
| Long-term results of ACL revision surgery using Achilles tendon allograft | — | Bologna | Recruiting | Mar 10, 2025 |
| Exercise with blood flow restriction for patients with complete ACL tears | — | Nicosia and 1 other locations | Recruiting | Dec 10, 2024 |
| Split-belt treadmill training to improve knee biomechanics after ACL reconstruction | — | Ann Arbor, Michigan | Recruiting | Jul 31, 2024 |
| Evaluating ACL injury and re-rupture rates after surgery | — | Milan | Recruiting | Jan 8, 2024 |
| Using living donor hamstring tendons for ACL reconstruction in children | — | Pembury, Kent | Recruiting | May 27, 2022 |
All recruiting trials (7)
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Ways to Boost Quadriceps Power After ACL Surgery
This study tests whether neuromuscular electrical stimulation or hamstring vibration can help people 2–4 months after ACL reconstruction increase their quadriceps strength.
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ACL reconstruction with the over-the-top technique plus lateral extra-articular tenodesis in older versus younger patients
This project tests whether ACL reconstruction using the over-the-top technique combined with lateral extra-articular tenodesis gives similar outcomes and complication rates in people over 50 compared with people under 30.
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Long-term results of ACL revision surgery using Achilles tendon allograft
This study tests how well revision ACL surgery using an Achilles tendon graft works for patients two years after their surgery and what factors might affect their recovery.
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Exercise with blood flow restriction for patients with complete ACL tears
This study is testing if exercising with blood flow restriction can help people with complete ACL tears recover better than just standard treatment alone.
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Split-belt treadmill training to improve knee biomechanics after ACL reconstruction
This small pilot will test whether six weeks of split-belt treadmill training can change how your reconstructed knee is loaded when you walk.
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Evaluating ACL injury and re-rupture rates after surgery
This study looks at how often people who had ACL surgery from 2020 to 2030 experience re-injury and how their recovery affects their ability to return to sports and quality of life.
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Using living donor hamstring tendons for ACL reconstruction in children
This study is testing a new way to repair torn ACLs in kids by using hamstring tendons from a living parent to see if it helps them heal better than traditional methods.
Related topics
Quick answers
How many ACL clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in Italy (3 trials), United States (2 trials), United Kingdom (1 trial), Cyprus (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.