Weight-Bearing CT for Healing of Periprosthetic Knee Fractures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study uses weight-bearing CT imaging to evaluate fracture fixation and bone healing around a total knee arthroplasty. Eligible participants are adults 50–90 who recently underwent revision surgery for a distal femur fracture and can stand for a weight-bearing CT exam. The goal is to standardize fracture healing assessment and improve guidance for post-operative care and potential revisions. Imaging will focus on visualizing bone ingrowth and implant stability to help clinicians make more informed treatment decisions. The study is conducted at London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's in London, Ontario.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Recently underwent revision surgery for repair of a distal femur fracture surgery for total knee arthroplasty femoral component using a fracture fixation plate. Due to the study requiring the potential participant to be scanned \<1-week post-operation, the duration of "recently" will be defined as \<1 week post-operation.
* Age 50-90 years
* Body mass index up to 40kg/m2
* Able to provide informed consent
* Able and willing to do study assessments and follow instructions

Exclusion Criteria:

* Prior revision surgery on the targeted knee
* Does not understand English
* Undergoing and/or have undergone revision surgery for any other indication
* Received intramedullary nail or distal femur replacement
* Cannot independently stand on one leg in the weight-bearing CT during the inducible displacement exam

Where it's running

• London Health Sciences Centre Research Institute
  London, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Brent Lanting, MD — London Health Sciences Centre
• Study coordinator: Brent Lanting, MD
• Email: brent.lanting@lhsc.on.ca
• Phone: 519-685-8500

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.