Clinical trial Recruiting at 1 site Observational Ages 50 to 85

Web-based program to identify individuals at risk for Alzheimer's disease

Official title: Alzheimer Prevention Trials (APT) Webstudy

Run by University of Southern California · NCT03638583 · Data updated 2026-11-12

This study is testing a web-based program to find people at higher risk for Alzheimer's disease so they can be invited to join clinical trials for new treatments.

Quick facts

Study typeObservational
Ages50 Years to 85 Years
SexAll
Enrollment200000 (estimated)
SponsorUniversity of Southern California
Academic / other
Locations1 site (San Diego, California)
StatusRecruiting
StartedDecember 20, 2017
Main results expectedApril 30, 2026
Study endsApril 30, 2026
Registry record updatedJuly 16, 2025
Trial IDNCT03638583 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 50 and older who show no signs of dementia and are willing to participate in remote cognitive testing.

Probably not a fit

Patients who already have a diagnosis of dementia will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Alzheimer Prevention Trials (APT) Webstudy aims to enhance enrollment in Alzheimer's disease clinical trials by identifying individuals at higher risk for developing dementia. Participants will register online, complete cognitive tests, and provide demographic information. They will return quarterly for follow-up assessments, and based on their risk scores, some may be invited for in-person evaluations at clinical trial sites. This approach combines web-based assessments with biomarker testing to refine the selection of high-risk individuals for further studies.

Why it matters

Potential benefit: If successful, this study could lead to earlier identification and intervention for individuals at risk of developing Alzheimer's disease.

How similar studies have gone: Other studies have shown promise in using web-based assessments for cognitive health, but this specific approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* male or female at least 50 years of age
* no evidence of dementia
* willing to participate in remote longitudinal cognitive testing and possible referral for biomarker assessment based on risk

Exclusion Criteria:

* N/A. Anyone can register for the APT Webstudy, however, only individuals identified using the risk algorithm will be referred for in-person biomarker assessments.

Where it's running

  • Https://Www.Aptwebstudy.Org
    San Diego, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.