Wearable sensors to track tremor and daily movement in Parkinson’s disease and essential tremor

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will recruit up to 60 adults with Parkinson’s disease or essential tremor to wear inertial sensors during clinic assessments and at home for 3, 7, or 21 days. Data from the wearables will be analyzed offline to describe movement features and explore their relationship to clinical assessments and medication timing. The study is exploratory and will not change care, diagnose conditions, assess treatments, or determine device performance. Participants will complete brief logs and attend a single clinic visit.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged 18 years or older.
2. Clinical diagnosis of idiopathic Parkinson's disease (Hoehn and Yahr stage I-III) or essential tremor.
3. Motor or tremor symptoms confirmed on clinical assessment.
4. Able to walk at least 4 metres independently, with or without a walking aid.
5. Able to provide written informed consent and comply with study procedures.
6. Willing and able to wear the study sensors in clinic and, where applicable, at home.
7. Able to understand study information and complete study materials in English.

Exclusion Criteria:

1. A recent major cardiovascular or cerebrovascular event, or another unstable condition that would make participation unsafe.
2. An uncontrolled psychiatric disorder, ongoing substance misuse, active systemic cancer treatment, or another serious illness likely to interfere with participation.
3. Pregnancy at enrolment.
4. Active skin disease or known allergy to adhesive plaster at anticipated sensor sites.
5. Dementia with Lewy Bodies, atypical, vascular, or drug-induced parkinsonism.
6. Previous invasive neuromodulation or neurosurgery for a movement disorder, including deep brain stimulation.
7. Current or recent participation in another interventional study that could affect safety or study outcomes.
8. In the investigator's opinion, unable to complete the study procedures safely.

Where it's running

• Clinical Research Facility, Western General Hospital, NHS Lothian
  Edinburgh, Edinburgh, United Kingdom Recruiting

Study contacts

• Principal investigator: Gordon Duncan — NHS Lothian
• Study coordinator: Gordon Duncan
• Email: gordon.duncan2@nhs.scot
• Phone: +44 131 537 3804

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• UX-DA003 injections for Parkinson's disease

  This early-phase trial tests whether injecting UX-DA003 is safe and may help motor symptoms in people with Parkinson's whose response to standard treatments has declined.

  Recruiting Early Phase 1 The First Affiliated Hospital of Anhui Medical University · Hefei, Anhui · NCT07911670

• Strength and dual-task training to help people with Parkinson’s improve strength and function

  This trial tests three levels of physiotherapy, including progressive resistance training with and without cognitive dual-task and instability components, to see if they improve muscle strength, body composition, and physical function in adults with Parkinson’s or related syndromes.

  Recruiting University of Valencia · Valencia, Valencia · NCT07907302

• Spinal Mobility, Rigidity, and Kinesiophobia in Parkinson's Disease with and without TMD

  This study tests whether people with Parkinson's disease who have Temporomandibular Disorders differ in spinal mobility, axial rigidity, and kinesiophobia from those without TMD.

  Recruiting Mustafa Kemal University · Hatay · NCT07850674

• A 12-Week Trial of Flexilev with the OraFID Device and App for Parkinson's

  This study tests whether taking small, precise doses of Flexilev with the OraFID dosing device and Levilog app is acceptable and helps people with Parkinson's manage their medicine.

  Recruiting at 2 sites Phase 4 Navamedic AB · Stockholm, Stockholm County and 4 other locations · NCT07839793

• Integrated Motor-Cognitive Training in Parkinson's Disease

  This study tests a combined motor and cognitive rehabilitation program to see if people with Parkinson’s disease can stick with it and show early signs of benefit.

  Recruiting University Hospital of Ferrara · Ferrara, FE · NCT07833748

• VIM0423 for Parkinson's Tremor in Adults Not Fully Controlled by Dopaminergic Therapy

  A Vima Therapeutics study tests whether the oral drug VIM0423 can reduce tremor in adults with Parkinson’s disease who still have tremor despite dopaminergic treatment.

  Recruiting at 4 sites Phase 2 Vima Therapeutics · Scottsdale, Arizona and 29 other locations · NCT07804615

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.