Voice biomarkers for Long COVID monitoring using the Long COVID Companion app
Official title: Unravelling Health and Frequent Symptoms and Voice Characteristics Evolution Over Time of Users of the Long COVID Companion Application to Develop Voice Biomarkers of Frequent Long Covid-related Symptoms
Run by Luxembourg Institute of Health · NCT07156994 · Data updated 2026-11-12
This study tests whether voice biomarkers collected through the Long COVID Companion app can reflect common Long COVID symptoms to help monitor patients remotely.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Luxembourg Institute of Health Government |
| Locations | 1 site (Strassen) |
| Status | Recruiting |
| Started | December 15, 2025 |
| Main results expected | September 30, 2028 |
| Study ends | September 30, 2028 |
| Registry record updated | September 15, 2026 |
| Trial ID | NCT07156994 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with Long COVID or persisting COVID-19 symptoms who can provide consent and speak English, French, or German.
✕Probably not a fit
Individuals without Long COVID symptoms or whose symptoms do not correspond to voice biomarkers may not see direct benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will use data from the Long COVID Companion app to identify voice-based signals associated with Long COVID symptoms such as fatigue, brain fog, and respiratory issues. It is an observational cohort study with no active intervention, collecting voice recordings alongside health-related data from adults with Long COVID or related symptoms. The goal is to develop vocal biomarker candidates that could enable remote monitoring and better understanding of symptom patterns over time. Participants will contribute voice samples and health information in English, French, or German, with informed consent. The study is led by the Luxembourg Institute of Health, with data collection at LIH in Strassen, Luxembourg.
Why it matters
Potential benefit: If successful, participants may benefit from improved remote monitoring and a better understanding of their symptom patterns through voice-based insights.
How similar studies have gone: There is prior work suggesting voice signals can reflect health status, but this approach for Long COVID biomarkers is exploratory and relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult (≥18 years old) * Male or female * People with persisting symptoms related to COVID-19 (With Long COVID diagnosis or not) * Adequate understanding of one of the study languages (English, French, German) * Electronically signed informed consent form Exclusion Criteria: ● No specific exclusion criteria
Where it's running
-
Lih
Strassen, Luxembourg Recruiting
Study contacts
- Study coordinator: Aurélie FISCHER, PhD
- Email: aurelie.fischer@lih.lu
- Phone: 00 352 26970230
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.