Vision outcomes after PTK-PRK using the CZM MEL 90 excimer laser
Official title: Clinical Data Collection of Myopic Patients After PTK-PRK With CZM MEL 90 Excimer Laser for Verification of Predicted Refractive Outcome Using EpiMaster Software Considering Epithelial Remodelling
Run by London Vision Clinic · NCT06996353 · Data updated 2026-11-12
This project will see if the EpiMaster app's predicted vision results match actual outcomes after PTK-PRK using the CZM MEL 90 laser for people with myopia or myopia plus astigmatism.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | London Vision Clinic Academic / other |
| Locations | 2 sites (Chandigarh, Punjab Haryana and 1 other locations) |
| Status | Recruiting |
| Started | May 26, 2025 |
| Main results expected | November 2026 |
| Study ends | June 2027 |
| Registry record updated | January 9, 2026 |
| Trial ID | NCT06996353 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with myopia (with or without astigmatism) scheduled for PTK-PRK with the CZM MEL 90 laser who can provide informed consent and complete follow-up visits.
✕Probably not a fit
Patients with ocular conditions excluded by the CZM MEL 90 user manual or those not undergoing PTK-PRK (including non-myopic refractive errors) are unlikely to benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational investigation collects routine postoperative clinical data from patients who undergo PTK-PRK with the CZM MEL 90 excimer laser and compares those results to preoperative predictions produced by the EpiMaster software. EpiMaster is not used to guide treatment in this project; its predictions are compared retrospectively to clinical refractive outcomes. Inclusion and exclusion follow the CZM MEL 90 user manual, and enrolled patients must be able to consent and complete scheduled follow-up visits. The work is sponsored by London Vision Clinic with Optana GmbH as collaborator and is conducted at participating eye clinics in India.
Why it matters
Potential benefit: If successful, this could improve clinicians' ability to predict refractive outcomes after PTK-PRK, leading to more accurate treatment planning and clearer patient expectations.
How similar studies have gone: Prediction tools and nomograms for refractive surgery have shown moderate success, but direct validation of the EpiMaster application specifically for PTK-PRK is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion criteria are according to the user manual of CZM MEL 90 Excimer Laser for treatment of refractive errors * Patient present with myopic or myopic and astigmatic error * Patient will be able to understand the patient information and willing to sign an informed consent * Patient will be willing to comply with all follow-up visits and the respective examinations Exclusion Criteria: * Exclusion criteria are according to the user manual of CZM MEL 90 Excimer Laser for treatment of refractive errors
Where it's running
-
Pro Sight Eye Hospital
Chandigarh, Punjab Haryana, India Recruiting -
Uma Eye Clinic
Chennai, Tamil Nadu, India Recruiting
Study contacts
- Principal investigator: Sheetal Brar, MD — Pro Sight Eye Hospital, Chandigarh, India
- Study coordinator: Timothy Archer, PhD
- Email: timothy@londonvisionclinic.com
- Phone: +44 02072241005
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.