How 3D face and jaw shape relates to nearsightedness and farsightedness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a cross-sectional observational study of about 120 healthy participants aged 21–25 that compares detailed ocular biometry (including axial length and other internal eye measurements) with three-dimensional craniofacial morphometric data. Participants will be divided into three groups—myopes, emmetropes, and hyperopes—with roughly equal numbers and balanced by sex, and only individuals of the same ethnic background will be included to limit population-related variability. Examinations include objective autorefractometry confirmed by subjective refraction, full anterior and posterior segment exams, and 3D imaging of maxillomandibular structures; people with prior ocular or facial surgery, craniofacial anomalies, certain orthodontic histories, trauma, strabismus, amblyopia, or systemic conditions affecting facial/ocular morphology are excluded. The design aims to identify whether specific facial shape features correlate with refractive status after growth is complete.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Healthy young adults aged 21 to 25 years.

Same ethnic background (to reduce population-related morphological variability).

Best-corrected visual acuity ≥ 1.0.

Normal findings of the anterior and posterior ocular segments.

Refractive status determined by objective autorefractometry and confirmed by subjective refraction.

Body mass index (BMI) between 18.5 and 24.9 kg/m².

Willingness to participate and provision of written informed consent.

Exclusion Criteria:

Previous ocular surgery.

Previous facial surgery.

Craniofacial anomalies.

Active or previous orthodontic therapy that may affect maxillomandibular relationships.

Strabismus.

Amblyopia.

Ocular trauma.

Facial trauma.

Systemic diseases that may affect facial morphology or ocular biometric parameters.

Where it's running

• University of Zagreb School of Dental Medicine
  Zagreb, Croatia Recruiting

Study contacts

• Study coordinator: Maja Malenica Ravlić, MD
• Email: majamalenicaravlic@gmail.com
• Phone: +38598670083

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.