Virus interactions in hospitalized patients during winter seasons in Lyon
Official title: Virus-virus Interactions Among Patients Admitted to the Hospices Civils de Lyon, During 2022 to 2025 Winters Seasons
Run by Hospices Civils de Lyon · NCT07805590 · Data updated 2026-11-12
This study tests all virological results from hospitalized patients in Lyon during winter to see how different respiratory viruses may co-occur or exclude each other.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 114230 (estimated) |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Lyon, Rhone) |
| Status | Recruiting |
| Started | January 5, 2026 |
| Main results expected | May 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | September 4, 2026 |
| Trial ID | NCT07805590 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Hospitals in Lyon (Croix-Rousse) and Infective Agents Institute patients of any age with a virological test for a respiratory infection during winter periods 2022–2025.
✕Probably not a fit
Patients whose samples do not yield detectable viruses or whose illnesses are unrelated to co-infection dynamics may not benefit from findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study analyzes routine diagnostic virology results from patients admitted to Hospices Civils de Lyon during winter seasons from 2022 to 2025. It aims to describe how common co-detections or mutual exclusions occur among respiratory viruses and how these patterns relate to disease severity. The approach combines epidemiology, clinical observations, and in vitro findings to explore population-level virus–virus interactions and their potential impact on patient outcomes. The study uses data from routine care samples without experimental interventions. Results may help inform understanding of viral dynamics and guide public health insights for respiratory infections.
Why it matters
Potential benefit: If successful, the study could improve understanding of how co-infections influence illness and help clinicians anticipate patterns of respiratory viral activity.
How similar studies have gone: Previous work has shown both negative interactions (mutual exclusion) and complex dynamics between respiratory viruses, supporting the relevance of population-level analyses.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * \- Any virological result (positive or negative) following a biological sample taken as part of routine care within the HCLs for the purpose of diagnosing a respiratory infection in a hospitalised patient. * Patients of any age * Samples taken during the winter periods between 2022 and 2025. Exclusion Criteria: * na
Where it's running
-
Infective Agents Institute, Croix rousse Hospital
Lyon, Rhone, France Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) in Adults
This study tests and compares the immune responses and tolerability of the latest COVID-19 vaccines from Novavax and Pfizer/BioNTech in adults at risk for severe COVID-19.
-
Tracking respiratory viruses in healthcare and animal workers
This project will test whether regular virus checks and immune monitoring in healthcare and animal workers can find new or spreading respiratory viruses early.
-
Blood viscosity in ARDS: a look at how thick the blood is
This study tests whether blood viscosity is higher in adults with ARDS and whether viscosity relates to their breathing and blood flow issues.
-
Surgical Use of Efanoctocog alfa in Hemophilia A Patients
This observational study looks at how efanesoctocog alfa (Altuvoct) is used around surgery in people with hemophilia A to see if it helps control bleeding.
-
Sleep quality and its determinants during the liver transplant pathway
This study tests how sleep quality changes from before liver transplantation to six months after, in adults on the transplant waitlist at a single hospital.
-
Compare Trans-Stomal Bladder Lithotripsy Methods in Continent Catheterizable Urinary Reservoirs
This study looks at different ways to break up bladder stones in people with continent catheterizable urinary diversions to see which method works best when the normal route isn’t available.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.