Virtual tumor board for patients with cancer and serious mental illness

Adapting the Tumor Board Model for Mental Illness and Cancer: A Single Arm Pilot Trial

Not applicable Interventional Massachusetts General Hospital · NCT05837598

This study is testing a virtual meeting system for patients with serious mental illness who have cancer to see if it helps improve their treatment and support.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorMassachusetts General Hospital Academic / other
Locations1 site (Danvers, Massachusetts)
Trial IDNCT05837598 on ClinicalTrials.gov

What this trial studies

This study investigates the feasibility and acceptability of a virtual tumor board designed for patients with serious mental illness (SMI) who have recently been diagnosed with cancer. It aims to improve access to psycho-oncology and oncology expertise, enhance clinician communication, and address barriers to care. The intervention includes proactive identification of patients, bi-monthly virtual meetings, and collaborative planning for patient care. The study will assess changes in cancer treatment, psychiatric symptoms, and clinician confidence in managing this dual diagnosis population.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with serious mental illness and a new diagnosis of invasive cancer.

Not a fit: Patients with cognitive impairments that prevent informed consent or those with recurrent cancer may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve cancer care and mental health outcomes for patients with serious mental illness.

How similar studies have performed: While virtual tumor boards have shown success in improving cancer care, this specific adaptation for mental illness and cancer is novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 18 years old
2. Verbal fluency in English
3. SMI (schizophrenia spectrum disorder, bipolar disorder, or major depressive disorder with either prior psychiatric hospitalization, history of suicide attempt/suicidal ideation, Medicaid insurance, and/or comorbid alcohol or opioid use disorder) confirmed by diagnostic evaluation of study psychiatrist
4. New invasive stage I-IV breast, lung, gastrointestinal, genitourinary, or head and neck cancer (highly suspected or confirmed according to documentation by the oncologist or pathology)
5. Oncology consultation at or referral to a MGH Danvers within the past 8 weeks

Exclusion Criteria:

1. Have cognitive impairment severe enough to interfere with completing brief study assessments or providing informed consent and does not have a guardian who can provide consent
2. Recurrence of same cancer type
3. Do not have verbal fluency in English

Where this trial is running

Danvers, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerSevere Major DepressionSchizophreniaBipolar DisorderLung CancerBreast CancerHead and Neck CancerGastrointestinal Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.