Bone plate design for mandible fractures: patient-specific versus conventional plates

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, parallel-group study compares patient-specific titanium plates designed from preoperative CT data with conventional plates that are shaped during surgery for mandibular body fractures. Bone mineral density at the fracture site will be measured by CT-derived Hounsfield Units at baseline and six months after surgery. All procedures follow a standardized surgical protocol performed by a single surgical team under general anesthesia. The primary outcome is the recovery of bone density at the fracture site, aiming to determine if CAD/CAM customization improves osseous healing compared with traditional plating.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Unilateral or bilateral mandibular body fracture requiring open reduction and internal fixation (ORIF), presenting either isolated or concurrently with other maxillofacial, midface, or other mandibular fractures.
* Patients in good general health who are medically cleared to undergo major maxillofacial surgery under general anesthesia.

Exclusion Criteria:

* Presence of comminuted fractures or pre-existing malunions at the fracture site.
* Patients with high-risk systemic diseases or any medical conditions that contraindicate the administration of general anesthesia.

Where it's running

• Faculty of Dentistry- Cairo University
  Cairo, Giza Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Dina Y Girgis — Assistant Lecturer
• Study coordinator: Dina Y Girgis
• Email: dina.yacoub@dentistry.cu.edu.eg
• Phone: 01278061226

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Platelet-rich plasma for jaw fracture healing

  This trial tests whether using a patient’s own PRP during jaw fracture surgery helps the upper or lower jaw bones heal faster and denser than surgery alone.

  Recruiting CMH Lahore Medical College and Institute of Dentistry · Lahore, Punjab Province and 1 other locations · NCT07930026

• Custom-made Titanium Plates vs Custom-made PEEK Plates for mandible fractures

  This study tests whether custom-made titanium or custom-made PEEK plates work better to fix mandibular fractures in adults 18 to 50.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07850570

• Safety-zone for cheek-access mandibular fracture fixation to protect facial nerve

  This study tests whether using a defined facial-safety zone during transbuccal access for fixing mandibular fractures helps protect the facial nerve.

  Recruiting Delta University for Science and Technology · Al Mansurah, Addakahlyia · NCT07807813

• Arch bars and screws for fixing mandibular fractures

  This study tests Erich arch bars, hybrid arch bars, and IMF screws to see which method best helps people with mandibular fractures achieve proper jaw alignment.

  Recruiting Mansoura University · Al Mansurah and 1 other locations · NCT07153120

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.