Venous Tourniquet with Low-Dose Sugammadex vs Arterial Tourniquet for Seizure Monitoring During ECT

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, open-label trial uses a within-subject design to compare two seizure monitoring approaches during ECT. After anesthesia and neuromuscular blockade, one arm receives an arterial tourniquet while the other arm uses a venous tourniquet with a regional low-dose sugammadex to partially reverse paralysis locally. Outcomes focus on seizure visibility and duration in each limb, as well as patient comfort and hemodynamic responses. The study aims to determine whether the venous tourniquet with sugammadex provides comparable or superior monitoring without the systemic side effects of IFT. Enrollment targets 40 adults with mood or psychotic disorders and ASA I-III, across Istanbul Medipol University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients scheduled for elective Electroconvulsive Therapy (ECT).
* ASA (American Society of Anesthesiologists) physical status I to III.

Exclusion Criteria:

* Known neuromuscular diseases (e.g., Myasthenia Gravis).
* Known allergy or hypersensitivity to sugammadex, rocuronium, ketamine, dexmedetomidine, or propofol.
* Presence of venous insufficiency, lymphedema, or active infection in the upper extremities.
* Severe cardiovascular instability.

Where it's running

• Istanbul Medipol University
  Istanbul, Turkey (Türkiye) Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.