Genetic counselling to prevent mental health issues from cannabis use

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to provide genetic counselling to young individuals aged 12 to 21 who are at risk of developing severe mental illnesses due to cannabis use. By identifying genetic factors that increase vulnerability to mental health issues, the study seeks to educate participants on their genetic predispositions and the associated risks of cannabis use. Participants will receive counselling from a board-certified genetic counsellor and may learn about their genotype, which could inform their decisions regarding cannabis consumption. The goal is to prevent the onset of severe mental illnesses such as schizophrenia, bipolar disorder, and major depressive disorder.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Enrolment in the Families Overcoming Risks and Building Opportunities for Well-being (FORBOW) study.
* Age between 12 and 21 years.
* Knowledge of English sufficient to benefit from the intervention.
* Capacity to provide informed consent at most recent FORBOW assessment.
* Provision of consent to be contacted about future studies at most recent FORBOW assessment.

Exclusion Criteria:

* A diagnosis of severe mental illness (psychotic disorder, bipolar disorder, severe/recurrent depression) at baseline
* Autism or intellectual disability of a degree that interferes with assessment (IQ \< 70)

Where it's running

• Nova Scotia Health Authority
  Halifax, Nova Scotia, Canada Recruiting

Study contacts

• Principal investigator: Rudolf Uher, MD, PhD — Nova Scotia Health Authority, Dalhousie University
• Study coordinator: Rudolf Uher, MD, PhD
• Email: uher@dal.ca
• Phone: 902-473-7209

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.