Vaccination against COVID-19 for patients with chronic kidney disease
Observational Study on the Effects of SARS-CoV-2 Vaccination in Dialysis and Kidney Transplant Patients
This study is testing how well the COVID-19 vaccine works for people with chronic kidney disease who are on dialysis or have had a kidney transplant.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Heinrich-Heine University, Duesseldorf Academic / other |
| Locations | 5 sites (Düsseldorf and 4 other locations) |
| Trial ID | NCT04743947 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enroll patients receiving dialysis or those who have undergone kidney transplantation to assess their response to COVID-19 vaccination. Given the increased risk of severe illness from COVID-19 in these populations, the study will analyze the effectiveness of the vaccine in immunocompromised individuals. By monitoring vaccine responses in clinical practice, the study seeks to provide insights into how to better protect these patients against COVID-19. The findings could help inform future vaccination strategies for patients with chronic kidney disease.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 or older who are currently receiving dialysis or have undergone kidney transplantation.
Not a fit: Patients who are not capable of giving consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of vaccine efficacy in immunocompromised patients, leading to improved protection against COVID-19.
How similar studies have performed: Other studies have indicated challenges in vaccine response among immunocompromised patients, making this approach both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * receiving dialysis (hemodialysis or peritoneal dialysis) * capable of giving consent * age 18 or older Exclusion Criteria: - non-capable of giving consent
Where this trial is running
Düsseldorf and 4 other locations
- MVZ DaVita Rhein-Ruhr — Düsseldorf, Germany (Recruiting)
- KfH Kuratorium für Dialyse und Nierentransplantation e.V. — Düsseldorf, Germany (Recruiting)
- University Hospital Düsseldorf, Heinrich Heine University — Düsseldorf, Germany (Recruiting)
- Nephrocare Mettmann — Mettmann, Germany (Recruiting)
- Hospital Solingen — Solingen, Germany (Recruiting)
Study contacts
- Study coordinator: Johannes Stegbauer, MD
- Email: johannes.stegbauer@med.uni-duesseldorf.de
- Phone: +492118117502
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.