Using whole-body MRI to identify significant health issues in the general population

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the accuracy of whole-body magnetic resonance imaging (WB-MRI) in predicting clinically significant diagnoses among a diverse group of participants aged 18 and older. Up to 100,000 subjects will be recruited from multiple clinical sites across the United States, with careful adherence to inclusion and exclusion criteria. Participants will undergo WB-MRI scans, and data will be collected to assess the effectiveness of this screening method in identifying conditions such as cancer, metabolic diseases, aneurysms, and neurologic disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Each subject MUST:

  * Be\>=18 years of age at the time of enrollment.
  * Be able to read and understand provided procedural information for the study;
  * Be able and willing to follow all study procedures including proper breathing and body movement minimization while within the WB-MRI system;
  * Be willing and able to provide required clinical, demographic, medical history, and concomitant medications information;
  * Be able to provide financial payment in advance for reimbursement of the cost of the WBMRI acquisition procedure and interpretation;
  * Complete all required consent procedures.

Exclusion Criteria:

* Harbor within their bodies contraindicated medical devices including, but not limited to, implanted pacemakers, intracranial aneurysm clips, cochlear implants, drug infusion pumps, neurostimulators, bone growth stimulators, certain intrauterine contraceptive devices, non- MRI safe metals, etc.;

  * Self-certify that they are pregnant;
  * Be seeking to undergo WB-MRI as a subject in this study in lieu of other covered dedicated diagnostic imaging evaluations when such covered procedures represent more appropriate or standard-of-care procedures by context-specific clinical indication;
  * Be an employee of the study site or the sponsor;
  * Have a medical condition or serious intercurrent illness, or other circumstance that, in the Investigator's judgment, could jeopardize the candidate's safety as a study subject, or that could interfere with study objectives.

Where it's running

• Hercules Research Center
  Watertown, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Perry Kaneriya, MD, MBA — Hercules
• Study coordinator: Kayla MacLeod, BS
• Email: kayla.macleod@herculesstudy.org
• Phone: (301) 450-4451

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.