Using Vitamin D to Boost Quadricep Strength After ACL Injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of Vitamin D3 supplementation on quadriceps muscle strength in patients recovering from anterior cruciate ligament (ACL) reconstruction. The study focuses on individuals aged 18-40 who have experienced a unilateral ACL injury and have low pre-operative serum vitamin D levels. Participants will be randomly assigned to receive either Vitamin D3 or a placebo, with the aim of determining if Vitamin D can enhance muscle mass and strength during rehabilitation. The trial seeks to address the persistent quadriceps muscle atrophy that affects recovery outcomes and return-to-play criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged 18-40 with unilateral ACL injury
2. Sporting injury with a Tegner score of 7
3. Pre-op serum vitamin D level \<20 ng/ml
4. 4 months post-ACLR with serum Vitamin D level remained \<20ng/ml
5. LSI for quadriceps strength \<70% of contralateral leg at 4-month isokinetic assessment
6. Both knees without history of injury/prior surgery

Exclusion Criteria:

1. Concomitant bone fracture, major meniscus injury or full-thickness chondral injuries requiring altered rehabilitation program post-operatively
2. Pre-operative radiographic signs of arthritis
3. Metal implants that would cause interference on MRI
4. Non-HS graft for ACLR
5. Patient non-compliant to the rehabilitation program
6. Regular sunbed users

Where it's running

• The Chinese University of Hong Kong
  Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Michael Tim-Yun Ong
• Email: michael.ong@cuhk.edu.hk
• Phone: 26364171

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.