Using vancomycin powder to prevent infections after inguinal lymph node dissection

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot randomized control trial aims to evaluate the effectiveness of intrawound vancomycin powder in reducing postoperative complications in women undergoing inguinal lymph node dissection for vulvar cancer. Participants will be randomly assigned to receive either vancomycin powder or no treatment during surgery. The primary focus is on measuring the rate of postoperative complications, including surgical site infections and hospital readmissions, within 30 days post-surgery. Secondary objectives include monitoring for seroma or lymphocele development and documenting any adverse events related to the treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women who are undergoing inguinal lymph node dissection for vulvar dysplasia
* Women with a prior lymph node dissection \>30 days before
* Women undergoing either a sentinel lymph node biopsy or full lymphadenectomy in a unilateral or bilateral groin dissection

Exclusion Criteria:

* Known allergy to vancomycin
* Known resistance to vancomycin

Where it's running

• Women and Infants Hospital
  Providence, Rhode Island, United States Recruiting

Study contacts

• Principal investigator: Jessica DiSilvestro, MD — Women & Infants Hospital
• Study coordinator: Jessica DiSilvestro, MD
• Email: jdisilvestro@wihri.org
• Phone: 401-274-1100

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.